Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.53 |
| ▸ | CNR2 | P34972 | 2/20 | 0.53 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | KDM5A | P29375 | 2/20 | 0.45 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | KDM5C | P41229 | 1/20 | 0.45 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.44 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9609205 | 0.82 | HTR7 (0.58) | CNR1CNR2HTR7SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL34463091 | 0.79 | KDM4D (0.55) | AKR1C3KDM5AKDM5BKDM4EKDM5C | |
| SCHEMBL4314900 | 0.79 | CSNK2A2 (0.48) | CNR1CNR2MRGPRX4AKR1C3CSNK2A2 | |
| SCHEMBL5258590 | 0.79 | SMN1; SMN2 (0.50) | MEN1NPC1MITFNFKB1RAB9A | |
| SCHEMBL2196514 | 0.75 | KDM5A (0.77) | KDM5AKDM5BKDM4EKDM5CCSNK2A2 | |
| SCHEMBL23291905 | 0.75 | ALDH1A1 (0.49) | CNR1KDM5AKDM5BKDM4CHDAC1 | |
| SCHEMBL27687664 | 0.74 | MRGPRX4 (0.50) | MRGPRX4KDM5AKDM5BKDM4EKDM5C | |
| SCHEMBL21593125 | 0.74 | CYP1A2 (0.51) | KDM4EKDM4CHTR7MEN1NPC1 | |
| SCHEMBL20564558 | 0.74 | CCNC (0.47) | HTR7SMN1; SMN2 | |
| SCHEMBL34463081 | 0.72 | NR3C2 (0.57) | MRGPRX4AKR1C3KDM5AKDM5BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104822380-A | Novel 4,6-disubstituted aminopyrimidine derivatives | VIROSTATICS SRL | 2015-08-05 | — | — | CN | disclosed |