Orthocresol

Orthocresol

SCHEMBL28023316

Cc1ccccc1O.OCCOCCO

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.42
MAPK1 P28482 1/20 0.42
TRPA1 O75762 2/20 0.41
ATM Q13315 1/20 0.41
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C19 P33261 1/20 0.41
IDO1 P14902 1/20 0.39
ALDH1A1 P00352 6/20 0.39
RECQL P46063 2/20 0.39
MAPT P10636 3/20 0.38
LMNA P02545 3/20 0.38
JAK2 O60674 1/20 0.38
GAA P10253 1/20 0.38
HTT P42858 2/20 0.37
CA2 P00918 2/20 0.36
KDM4E B2RXH2 1/20 0.36
NPC1 O15118 1/20 0.36
CA12 O43570 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetraethylene Glycol SCHEMBL9310030 0.91 ALDH1A1 (0.43) TSHRMAPK1TRPA1ATMMEN1
O-Xylene SCHEMBL27533464 0.87 TSHR (0.50) TSHRMAPK1MEN1KMT2ACYP1A2
Tetraethylene Glycol SCHEMBL9860297 0.85 MEN1 (0.52) TSHRMAPK1MEN1KMT2AALDH1A1
Catechol SCHEMBL3905550 0.84 ALDH1A1 (0.53) TSHRMAPK1MEN1KMT2AIDO1
Catechol SCHEMBL6689005 0.84 ALDH1A1 (0.53) TSHRMAPK1MEN1KMT2AIDO1
Orthocresol SCHEMBL7088805 0.84 TRPA1 (0.50) TSHRMAPK1TRPA1ATMMEN1
Orthocresol SCHEMBL27258627 0.82 TSHR (0.40) TSHRMAPK1TRPA1ATMMEN1
Orthocresol SCHEMBL10343638 0.80 TSHR (0.43) TSHRTRPA1ATMCYP1A2CYP2C19
Orthocresol SCHEMBL27625293 0.80 TRPA1 (0.50) TSHRMAPK1TRPA1ATMMEN1
Orthocresol SCHEMBL2814754 0.79 TRPA1 (0.55) TSHRMAPK1TRPA1ATMMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104877737-A Emulsification cutting fluid for special aerospace equipment material, preparation method and uses thereof SHANGHAI PETROFER SPECIAL LUBRICATING AGENT CO LTD 2015-09-02 CN disclosed