Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14052421 | 0.94 | PTGS1 (0.47) | TDP1POLBSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL4496590 | 0.85 | CNR1 (0.42) | TDP1POLBSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL5542570 | 0.83 | TDP1 (0.55) | TDP1POLBSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL649228 | 0.82 | POLB (0.39) | POLBSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL31098887 | 0.82 | EPHX1 (0.63) | MEN1KMT2AEPHX1NAAA | |
| SCHEMBL11922844 | 0.81 | TDP1 (0.58) | TDP1POLBSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL22351756 | 0.81 | EPHX1 (0.52) | POLBSMN1; SMN2ALDH1A1EPHX1 | |
| SCHEMBL2138113 | 0.80 | DNM1 (0.46) | POLBALDH1A1MEN1KMT2ACA14 | |
| SCHEMBL2747680 | 0.79 | TDP1 (0.52) | TDP1POLBSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL19183222 | 0.79 | ADRA1A (0.58) | POLBSMN1; SMN2MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9765169-B2 | Functionalized polymer hybrids | CARNEGIE MELLON UNIVERSITY (US) | 2017-09-19 | — | — | US | disclosed |
| US-20120016082-A1 | CONJUGATION REACTIONS | BIOCOMPATIBLES UK LIMITED (GB) | 2012-01-19 | — | — | US | disclosed |
| US-8053520-B2 | Conjugation reactions | BIOCOMPATIBLES UK LIMITED (GB) | 2011-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016082-A1 | CONJUGATION REACTIONS | PHPT1, GNE, MGMT | TDP1 2747/4885POLB 284/4885SMN1; SMN2 3385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.