Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRK6 | P43250 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | GFER | P55789 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28142437 | 0.81 | MAPKAPK2 (0.38) | GRK6MEN1KMT2AMAPTPOLB | |
| SCHEMBL27686118 | 0.77 | ALDH1A1 (0.44) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL29844491 | 0.74 | ALDH1A1 (0.38) | MEN1KMT2AKDM4EMAPTLMNA | |
| SCHEMBL940110 | 0.74 | ALDH1A1 (0.38) | MEN1KMT2AKDM4EMAPTLMNA | |
| SCHEMBL28024021 | 0.73 | ALDH1A1 (0.49) | MEN1KMT2AKDM4EMAPTGFER | |
| SCHEMBL27930550 | 0.73 | GRK6 (0.41) | GRK6MEN1KMT2AKDM4EMAPT | |
| SCHEMBL28271273 | 0.72 | NPC1 (0.37) | MEN1KMT2AMAPTLMNAPOLB | |
| SCHEMBL27973252 | 0.72 | AHR (0.47) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL68805 | 0.71 | MAOA (0.52) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL27478488 | 0.70 | KMT2A (0.45) | MEN1KMT2AMAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104870438-A | SECA inhibitors and methods of making and using the same | UNIV GEORGIA STATE RES FOUND | 2015-08-26 | — | — | CN | disclosed |