Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK2 | Q9HBH9 | 6/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.41 |
| ▸ | EIF4E | P06730 | 1/20 | 0.41 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14614677 | 0.75 | MKNK2 (0.43) | MKNK2MKNK1CLK4EIF4ESTK17A | |
| SCHEMBL9777679 | 0.74 | MEN1 (0.55) | CCNA2CDK2ALDH1A1MAPK10NPC1 | |
| Hydrochloric Acid SCHEMBL10587715 | 0.72 | POLB (0.35) | POLBNPC1RAB9ANUDT1KDM4E | |
| SCHEMBL28949886 | 0.71 | ALDH1A1 (0.54) | CDK1CCNB1CCNA2CCNE1CDK2 | |
| SCHEMBL13064955 | 0.69 | CDK5 (0.61) | CLK4CDK1CCNB1CCNA2CCNE1 | |
| SCHEMBL15711333 | 0.69 | MAPK10 (0.62) | CDK1CCNB1CCNA2CCNE1CDK2 | |
| SCHEMBL7442860 | 0.69 | RAPGEF4 (0.50) | CDK1CCNB1CCNA2CCNE1CDK2 | |
| SCHEMBL31247403 | 0.69 | SYK (0.42) | MKNK2MKNK1CLK4EIF4ESTK17A | |
| SCHEMBL31247573 | 0.68 | KDM4E (0.57) | CLK4CDK1CCNB1CCNA2CCNE1 | |
| SCHEMBL31247406 | 0.68 | CDK1 (0.48) | CLK4CDK1CCNB1CCNA2CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103121972-B | As the pyrimidine urea derivatives of kinase inhibitor | NOVARTIS AG (CH) | 2015-07-29 | — | — | CN | disclosed |