Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GRK2 | P25098 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 5/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28023022 | 0.92 | TDP1 (0.57) | HSD11B1HPGDNPC1RAB9ATDP1 | |
| SCHEMBL14336043 | 0.89 | TDP1 (0.59) | HSD11B1TDP1LMNAMAPK1POLB | |
| SCHEMBL9723980 | 0.85 | NPC1 (0.56) | HSD11B1NPC1RAB9ATDP1LMNA | |
| SCHEMBL28023642 | 0.82 | LMNA (0.49) | HSD11B1NPC1RAB9ATDP1LMNA | |
| SCHEMBL27933090 | 0.80 | TDP1 (0.66) | HSD11B1TDP1LMNAMAPK1POLB | |
| SCHEMBL27785317 | 0.77 | TDP1 (0.66) | NPC1RAB9ATDP1LMNAMAPK1 | |
| SCHEMBL14578755 | 0.77 | KMT2A (0.57) | HPGDLMNAKMT2AALDH1A1MAPT | |
| SCHEMBL27933192 | 0.77 | HSD11B1 (0.88) | HSD11B1GRK2RECQLPOLBCTDSP1 | |
| SCHEMBL28023012 | 0.77 | HPGD (0.48) | HPGDNPC1RAB9ATDP1LMNA | |
| SCHEMBL18775896 | 0.76 | HPGD (0.49) | HPGDNPC1RAB9ATDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103509135-B | Olefin polymerization catalyst component, preparation method and application thereof | CHINA PETROLEUM & CHEMICAL | 2015-07-22 | — | — | CN | disclosed |