Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28023650 | 0.92 | TDP1 (0.53) | LMNATDP1MAPTHSD11B1BCHE | |
| SCHEMBL14336043 | 0.85 | TDP1 (0.59) | LMNATDP1MAPTHSD11B1ALDH1A1 | |
| SCHEMBL9723980 | 0.85 | NPC1 (0.56) | LMNATDP1MAPTHSD11B1ALDH1A1 | |
| SCHEMBL28023649 | 0.82 | HSD11B1 (0.55) | LMNATDP1MAPTHSD11B1ALDH1A1 | |
| SCHEMBL28023633 | 0.82 | LMNA (0.47) | LMNATDP1MAPTBCHEALDH1A1 | |
| SCHEMBL18775826 | 0.79 | MEN1 (0.46) | LMNATDP1MAPTBCHEALDH1A1 | |
| SCHEMBL28023652 | 0.78 | ALDH1A1 (0.49) | LMNATDP1MAPTALDH1A1MAPK1 | |
| SCHEMBL14578755 | 0.77 | KMT2A (0.57) | LMNAMAPTALDH1A1CA9PKM | |
| SCHEMBL27933090 | 0.77 | TDP1 (0.66) | LMNATDP1MAPTHSD11B1ALDH1A1 | |
| SCHEMBL28023017 | 0.75 | ALDH1A1 (0.46) | LMNATDP1MAPTALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103509135-B | Olefin polymerization catalyst component, preparation method and application thereof | CHINA PETROLEUM & CHEMICAL | 2015-07-22 | — | — | CN | disclosed |