SCHEMBL28023682

SCHEMBL28023682

Brc1ccc(-c2ccccc2-c2ccccc2)cc1.c1cnnnc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.54
MAPK1 P28482 2/20 0.54
NPC1 O15118 3/20 0.44
RAB9A P51151 3/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
NFKB1 P19838 1/20 0.44
NFKB2 Q00653 1/20 0.44
RELA Q04206 1/20 0.44
NR1H4 Q96RI1 1/20 0.42
CDK2 P24941 2/20 0.40
CCNA2 P20248 1/20 0.40
TSHR P16473 2/20 0.40
TP53 P04637 1/20 0.40
MAPT P10636 1/20 0.40
HPGD P15428 1/20 0.40
DGAT1 O75907 1/20 0.40
NR1H2 P55055 1/20 0.40
NR1H3 Q13133 1/20 0.40
MAPK13 O15264 2/20 0.39
GCGR P47871 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16294953 0.87 NISCH (0.45) ALDH1A1MAPK1SMN1; SMN2TSHRMAPT
SCHEMBL2920544 0.87 NISCH (0.45) ALDH1A1MAPK1SMN1; SMN2TSHRMAPT
SCHEMBL29410298 0.85 ALDH1A1 (0.74) ALDH1A1MAPK1NPC1RAB9ASMN1; SMN2
SCHEMBL4825288 0.85 ALDH1A1 (0.74) ALDH1A1MAPK1NPC1RAB9ASMN1; SMN2
SCHEMBL27912462 0.83 GABRG2 (0.46) ALDH1A1MAPK1NPC1RAB9ASMN1; SMN2
SCHEMBL15705955 0.83 ALDH1A1 (0.79) ALDH1A1MAPK1NPC1RAB9ASMN1; SMN2
Hydrogen Sulfide SCHEMBL27833170 0.83 ALDH1A1 (0.70) ALDH1A1MAPK1NPC1RAB9ASMN1; SMN2
SCHEMBL27908015 0.83 ALDH1A1 (0.70) ALDH1A1MAPK1NPC1RAB9ASMN1; SMN2
SCHEMBL19125933 0.80 ALDH1A1 (0.63) ALDH1A1MAPK1NPC1RAB9ASMN1; SMN2
SCHEMBL7522172 0.80 ALDH1A1 (0.63) ALDH1A1MAPK1NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105121595-A Light emitting material and organic light emitting element using same NAT UNIV CORP KYUSHU UNIV 2015-12-02 CN disclosed