Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16294953 | 1.00 | NISCH (0.45) | NISCHALDH1A1HSD17B10HPGDBCL2L1 | |
| SCHEMBL28023682 | 0.87 | ALDH1A1 (0.54) | NISCHALDH1A1HPGDMAPK1NPSR1 | |
| Biphenyl SCHEMBL790630 | 0.86 | ALDH1A1 (0.56) | NISCHALDH1A1HSD17B10BCL2L1MAPK1 | |
| Biphenyl SCHEMBL418438 | 0.86 | ALDH1A1 (0.56) | NISCHALDH1A1HSD17B10BCL2L1MAPK1 | |
| Biphenyl SCHEMBL790623 | 0.86 | ALDH1A1 (0.56) | NISCHALDH1A1HSD17B10BCL2L1MAPK1 | |
| SCHEMBL18989242 | 0.84 | CYP2A6 (0.71) | ALDH1A1HPGDCYP2A6NOTUMPTGS2 | |
| 2-Phenylphenol SCHEMBL28165069 | 0.84 | HPGD (0.71) | ALDH1A1HSD17B10HPGDBCL2L1NPSR1 | |
| SCHEMBL29177893 | 0.83 | LMNA (0.37) | NISCHALDH1A1HSD17B10HPGDBCL2L1 | |
| SCHEMBL29211947 | 0.82 | GPR55 (0.45) | NISCHALDH1A1HSD17B10HPGDBCL2L1 | |
| SCHEMBL21447 | 0.80 | ALDH1A1 (0.61) | NISCHALDH1A1HSD17B10HPGDBCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8404705-B2 | Naphthalene amidine imides | BASF SE (DE) | 2013-03-26 | — | — | US | disclosed |
| EP-1907484-B1 | NAPHTHALENE AMIDINE IMIDES | BASF SE (DE) | 2010-09-29 | — | — | EP | disclosed |
| US-20100202984-A1 | Naphthalene amidine imides | BASF SE (DE) | 2010-08-12 | — | — | US | disclosed |
| EP-1907484-A1 | NAPHTHALENE AMIDINE IMIDES | Ciba Specialty Chemicals Holding, Inc. (CH) | 2008-04-09 | — | — | EP | disclosed |
| WO-2007012611-A1 | NAPHTHALENE AMIDINE IMIDES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2007-02-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100202984-A1 | Naphthalene amidine imides | NES, TXN2, NAT1 | NISCH 1556/4885ALDH1A1 1047/4885HSD17B10 3061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.