Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FADS1 | O60427 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 6/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 7/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | GLA | P06280 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 5/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29944962 | 0.76 | MAPT (0.50) | GAAALDH1A1MAPTTDP1LMNA | |
| SCHEMBL27945514 | 0.76 | AKT1 (0.40) | — | |
| SCHEMBL28023706 | 0.73 | MAPT (0.30) | MAPT | |
| SCHEMBL27727248 | 0.69 | MAOA (0.33) | GAAMEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL27945472 | 0.69 | MAPT (0.30) | MAPT | |
| SCHEMBL28024161 | 0.69 | MAPT (0.30) | MAPT | |
| SCHEMBL20658953 | 0.69 | SMN1; SMN2 (0.31) | MAPTSMN1; SMN2 | |
| SCHEMBL28324627 | 0.67 | GAA (0.38) | FADS1GAAPOLBMEN1KMT2A | |
| SCHEMBL28032286 | 0.66 | MEN1 (0.30) | MEN1KMT2AKDM4ELMNA | |
| SCHEMBL28031694 | 0.66 | MEN1 (0.30) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103370321-B | Kui Linpyrimido quinoline [1, the 2-b] indazole replaced and the purposes of the conditioning agent as PI3K/AKT approach thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-07-29 | — | — | CN | disclosed |