Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.36 |
| ▸ | CHRNA2 | Q15822 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28023719 | 0.76 | FADS1 (0.38) | MAPTMAPK1ALDH1A1GAATDP1 | |
| SCHEMBL4791231 | 0.71 | CHRNB2 (0.40) | MAPTHTTMAPK1CHRNB2CHRNA4 | |
| SCHEMBL28192142 | 0.69 | MAPT (0.44) | MAPTHTTMAPK1ALDH1A1GAA | |
| SCHEMBL27945514 | 0.68 | AKT1 (0.40) | — | |
| SCHEMBL27727248 | 0.67 | MAOA (0.33) | MAPTGAANPSR1 | |
| SCHEMBL20658953 | 0.67 | SMN1; SMN2 (0.31) | MAPTNPSR1 | |
| SCHEMBL28023706 | 0.67 | MAPT (0.30) | MAPTNPSR1 | |
| SCHEMBL27945472 | 0.67 | MAPT (0.30) | MAPTNPSR1 | |
| SCHEMBL28024161 | 0.67 | MAPT (0.30) | MAPTNPSR1 | |
| SCHEMBL28031694 | 0.64 | MEN1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232110-A | Fluorenone derivative with sandwich structure, preparation method thereof and organic light-emitting device | 广东工业大学 | 2022-10-25 | — | — | CN | disclosed |