Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.50 |
| ▸ | SMO | Q99835 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PHGDH | O43175 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6698026 | 0.85 | NAMPT (0.64) | NAMPTTSHRLMNAMAPK1USP2 | |
| SCHEMBL27550709 | 0.84 | NAMPT (0.62) | NAMPTTSHRLMNAMAPK1USP2 | |
| SCHEMBL6698019 | 0.81 | NAMPT (0.62) | NAMPTTSHRLMNAMAPK1USP2 | |
| SCHEMBL2320890 | 0.81 | GRM5 (0.57) | NAMPTTSHRMAPK1USP2SMN1; SMN2 | |
| SCHEMBL2760493 | 0.79 | NAMPT (0.53) | NAMPTTSHRLMNAMAPK1USP2 | |
| SCHEMBL13149183 | 0.79 | SLC6A7 (0.77) | TSHRLMNASMN1; SMN2KDM4ESLC6A7 | |
| SCHEMBL3634940 | 0.78 | HPGD (0.60) | NAMPTLMNAMAPK1USP2HTT | |
| SCHEMBL14409648 | 0.78 | KCNA5 (0.56) | NAMPTTSHRLMNAMAPK1USP2 | |
| SCHEMBL13504090 | 0.78 | MGLL (0.64) | NAMPTUSP2HTTSMN1; SMN2SLC6A7 | |
| SCHEMBL2740504 | 0.77 | SIGMAR1 (0.61) | NAMPTUSP2SMN1; SMN2SLC6A7SMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102971291-B | Novel amide derivative and use thereof as medicine | MITSUBISHI TANABE PHARMA CORP | 2015-07-22 | — | — | CN | disclosed |