SCHEMBL28024028

SCHEMBL28024028

NC(C(=O)O)(c1ccccc1)c1ccccc1.[NaH]

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.52
CYP2D6 P10635 1/20 0.52
KCNN4 O15554 4/20 0.48
MAPT P10636 2/20 0.46
KMT2A Q03164 1/20 0.46
HIF1A Q16665 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
TSHR P16473 2/20 0.41
ALDH1A1 P00352 1/20 0.41
CYP2C19 P33261 3/20 0.40
CYP2C9 P11712 1/20 0.40
KEAP1 Q14145 1/20 0.39
NFE2L2 Q16236 1/20 0.39
HDAC3 O15379 1/20 0.39
HDAC4 P56524 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC7 Q8WUI4 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC10 Q969S8 1/20 0.39
HDAC11 Q96DB2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL638306 0.97 CYP1A2 (0.54) CYP1A2CYP2D6KCNN4MAPTKMT2A
Hydrochloric Acid SCHEMBL27908053 0.95 CYP1A2 (0.52) CYP1A2CYP2D6KCNN4MAPTKMT2A
SCHEMBL4540929 0.85 KIF11 (0.47) CYP1A2CYP2D6KCNN4MAPTKMT2A
SCHEMBL28012260 0.85 ALDH1A1 (0.56) CYP1A2CYP2D6KCNN4MAPTKMT2A
SCHEMBL2482093 0.85 KIF11 (0.49) CYP1A2CYP2D6MAPTKMT2ASMN1; SMN2
Hydrochloric Acid SCHEMBL27841052 0.83 ALDH1A1 (0.54) CYP1A2CYP2D6KCNN4MAPTKMT2A
SCHEMBL4239216 0.80 CA1 (0.45) CYP1A2CYP2D6KCNN4MAPTKMT2A
SCHEMBL21219824 0.80 SMN1; SMN2 (0.56) CYP1A2CYP2D6HIF1ASMN1; SMN2CYP2C19
SCHEMBL8169066 0.80 MAPT (0.58) CYP1A2CYP2D6KCNN4MAPTKMT2A
Hydrochloric Acid SCHEMBL27841048 0.79 KCNN4 (0.58) CYP1A2CYP2D6KCNN4KMT2ACYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107952065-A Include the Insulin Aspart for being substituted anionic compound 阿道恰公司 2018-04-24 CN disclosed
CN-104902922-B Fast acting insulin formulations comprising substituted anionic compounds 阿道恰公司 2017-12-12 CN disclosed
CN-104902922-A Fast acting insulin formulations comprising substituted anionic compounds ADOCIA 2015-09-09 CN disclosed