Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27908053 | 0.97 | CYP1A2 (0.52) | CYP1A2CYP2D6KCNN4MAPTKMT2A | |
| SCHEMBL28024028 | 0.97 | CYP1A2 (0.52) | CYP1A2CYP2D6KCNN4MAPTKMT2A | |
| SCHEMBL28012260 | 0.87 | ALDH1A1 (0.56) | CYP1A2CYP2D6KCNN4MAPTKMT2A | |
| SCHEMBL4540929 | 0.87 | KIF11 (0.47) | CYP1A2CYP2D6KCNN4MAPTKMT2A | |
| SCHEMBL2482093 | 0.87 | KIF11 (0.49) | CYP1A2CYP2D6MAPTKMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27841052 | 0.85 | ALDH1A1 (0.54) | CYP1A2CYP2D6KCNN4MAPTKMT2A | |
| SCHEMBL21219824 | 0.82 | SMN1; SMN2 (0.56) | CYP1A2CYP2D6HIF1ASMN1; SMN2CYP2C19 | |
| SCHEMBL4239216 | 0.82 | CA1 (0.45) | CYP1A2CYP2D6KCNN4MAPTKMT2A | |
| SCHEMBL8169066 | 0.82 | MAPT (0.58) | CYP1A2CYP2D6KCNN4MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL27841048 | 0.81 | KCNN4 (0.58) | CYP1A2CYP2D6KCNN4KMT2ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 313 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2718281-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARMA SPA (IT) | 2015-09-09 | — | — | EP | claimed |
| US-20030198598-A1 | Polypeptide derivatives | ALBERT RAINER (CH) | 2003-10-23 | — | — | US | claimed |
| EP-0927168-B1 | 1,3-DIHETEROCYCLIC METALLOPROTEASE INHIBITORS | PROCTER & GAMBLE (US) | 2002-11-06 | — | — | EP | claimed |
| EP-0927161-B1 | SUBSTITUTED CYCLIC AMINE METALLOPROTEASE INHIBITORS | PROCTER & GAMBLE (US) | 2002-10-16 | — | — | EP | claimed |
| EP-0688315-B1 | PYRROLIDINE AND OXAZOLIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF THROMBOCYTE AGGREGATION | HOECHST AG (DE) | 1999-05-06 | — | — | EP | claimed |
| EP-0887374-A1 | Synthetic polyolefinic resin composition containing a clarifying nucleating agent | ELF ATOCHEM S.A. (FR) | 1998-12-30 | — | — | EP | claimed |
| EP-0436005-B1 | LABELED POLYPEPTIDE DERIVATIVES | SANDOZ LTD (CH) | 1995-03-29 | — | — | EP | claimed |
| US-5399570-A | Aspartic acid derivatives, and their use for inhibiting platelete aggregation | CASSELLA AKTIENGESELLSCHAFT (DE) | 1995-03-21 | — | — | US | claimed |
| EP-0182262-B1 | NONA AND DECAPEPTIDE ANALOGS OF LHRH USEFUL AS LHRH ANTAGONISTS | SYNTEX (U.S.A.) INC. (US) | 1993-01-20 | — | — | EP | claimed |
| US-5116817-A | LHRH preparations for intranasal administration | SYNTEX (U.S.A.) INC. (US) | 1992-05-26 | — | — | US | claimed |
| EP-0436005-A1 | LABELED POLYPEPTIDE DERIVATIVES. | SANDOZ LTD (CH) | 1991-07-10 | — | — | EP | claimed |
| WO-1991001144-A1 | LABELED POLYPEPTIDE DERIVATIVES | SANDOZ LTD (CH) | 1991-02-07 | — | — | WO | claimed |
| WO-1989009786-A1 | PEPTIDE DERIVATIVES | SANDOZ AG (CH) | 1989-10-19 | — | — | WO | claimed |
| EP-0097031-B1 | NONAPEPTIDE AND DECAPEPTIDE ANALOGS OF LHRH USEFUL AS LHRH ANTAGONISTS, THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | SYNTEX (U.S.A.) INC. (US) | 1988-09-21 | — | — | EP | claimed |
| US-4690916-A | ANTIFERTILITY AGENTS; HALO-SUBSTITUTED GUANADINO AMINO ACYL RESIDUE COMPONENT | SYNTEX (U.S.A.) INC. (US) | 1987-09-01 | — | — | US | claimed |
| EP-0111841-B1 | LHRH PREPARATIONS FOR INTRANASAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1987-05-06 | — | — | EP | claimed |
| EP-0182262-A2 | Nona and decapeptide analogs of LHRH useful as LHRH antagonists | SYNTEX (U.S.A.) INC. (US) | 1986-05-28 | — | — | EP | claimed |
| EP-0111841-A1 | LHRH preparations for intranasal administration | SYNTEX (U.S.A.) INC. (US) | 1984-06-27 | — | — | EP | claimed |
| EP-0097031-A2 | Nonapeptide and decapeptide analogs of LHRH useful as LHRH antagonists, their preparation and compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1983-12-28 | — | — | EP | claimed |
| US-4160818-A | Fluorimetric immunoassay for diphenylhydantoin | TECHNICON INSTRUMENTS CORPORATION (US) | 1979-07-10 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030198598-A1 | Polypeptide derivatives | HDGF, IGFBP1, VIP | CYP1A2 4869/4885CYP2D6 4828/4885KCNN4 4412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.