Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 4/20 | 0.44 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.44 |
| ▸ | TLR2 | O60603 | 5/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8090207 | 0.93 | LPAR1 (0.50) | LPAR1LPAR3TLR2LPAR2CYP1A2 | |
| SCHEMBL6914851 | 0.89 | LPAR1 (0.47) | LPAR1LPAR3TLR2LPAR2TSHR | |
| SCHEMBL11494461 | 0.87 | LPAR1 (0.41) | LPAR1LPAR3TLR2LPAR2CYP1A2 | |
| SCHEMBL30826314 | 0.86 | LPAR1 (0.59) | LPAR1LPAR3TLR2LPAR2 | |
| SCHEMBL10707922 | 0.85 | CYP1A2 (0.37) | CYP1A2MAPK1MEN1GMNNLMNA | |
| SCHEMBL8631854 | 0.84 | TSHR (0.39) | LPAR1LPAR3TLR2LPAR2CYP1A2 | |
| SCHEMBL2223328 | 0.83 | CYP1A2 (0.42) | CYP1A2MAPK1MEN1GMNNLMNA | |
| SCHEMBL28380343 | 0.81 | ALDH1A1 (0.45) | CYP1A2MAPK1MEN1GMNNLMNA | |
| SCHEMBL538789 | 0.81 | GPR84 (0.44) | TLR2CYP1A2MAPK1MEN1GMNN | |
| SCHEMBL14815623 | 0.81 | GPR84 (0.44) | CYP1A2MAPK1MEN1GMNNLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3460022-B1 | COMPOSITIONS WHICH CAN BE USED AS A REFRIGERANT | ARKEMA FRANCE (FR) | 2023-06-28 | — | — | EP | disclosed |
| EP-3460022-A1 | COMPOSITIONS WHICH CAN BE USED AS A REFRIGERANT | ARKEMA FRANCE (FR) | 2019-03-27 | — | — | EP | disclosed |
| EP-2092037-B1 | COMPOSITIONS THAT CAN BE USED AS REFRIGERANTS | ARKEMA FRANCE (FR) | 2018-07-25 | — | — | EP | disclosed |
| EP-2239309-A2 | Compositions which can be used as a refrigerant | Arkema France (FR) | 2010-10-13 | — | — | EP | disclosed |