Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PLA2G2C | Q5R387 | 4/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | PTAFR | P25105 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.36 |
| ▸ | PRKCA | P17252 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28007066 | 0.91 | ALDH1A1 (0.44) | ALDH1A1PLA2G2CADRA1DPTAFRHTR1D | |
| SCHEMBL11124575 | 0.86 | ALDH1A1 (0.42) | ALDH1A1PLA2G2CADRA1DPTAFRHTR1D | |
| SCHEMBL4070149 | 0.83 | TSHR (0.39) | ALDH1A1PRKCATSHR | |
| SCHEMBL9061242 | 0.83 | TSHR (0.46) | ALDH1A1PLA2G2CADRA1DPTAFRHTR1D | |
| SCHEMBL8143953 | 0.81 | TSHR (0.41) | USP2LPAR1LPAR3PRKCATSHR | |
| SCHEMBL28606066 | 0.80 | ADRA1D (0.52) | ALDH1A1PLA2G2CADRA1DPTAFRHTR1D | |
| SCHEMBL861924 | 0.80 | ALDH1A1 (0.36) | ALDH1A1PRKCATSHR | |
| SCHEMBL4400024 | 0.79 | ALDH1A1 (0.32) | ALDH1A1TSHR | |
| SCHEMBL11273920 | 0.79 | LPAR1 (0.32) | ALDH1A1PLA2G2CUSP2KDM4EALOX15 | |
| SCHEMBL28357447 | 0.77 | TSHR (0.43) | USP2LPAR1LPAR3PRKCATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3460022-B1 | COMPOSITIONS WHICH CAN BE USED AS A REFRIGERANT | ARKEMA FRANCE (FR) | 2023-06-28 | — | — | EP | disclosed |
| EP-3460022-A1 | COMPOSITIONS WHICH CAN BE USED AS A REFRIGERANT | ARKEMA FRANCE (FR) | 2019-03-27 | — | — | EP | disclosed |
| EP-2092037-B1 | COMPOSITIONS THAT CAN BE USED AS REFRIGERANTS | ARKEMA FRANCE (FR) | 2018-07-25 | — | — | EP | disclosed |
| EP-2239309-A2 | Compositions which can be used as a refrigerant | Arkema France (FR) | 2010-10-13 | — | — | EP | disclosed |