SCHEMBL861924

SCHEMBL861924

CCOC(COC)OC(C)=O

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.36
TSHR P16473 3/20 0.36
LMNA P02545 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TDP1 Q9NUW8 1/20 0.34
CHRM2 P08172 1/20 0.32
CHRM4 P08173 1/20 0.32
CHRM1 P11229 1/20 0.32
TBXA2R P21731 1/20 0.32
GALR3 O60755 1/20 0.31
MAPT P10636 1/20 0.31
BLM P54132 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
PRKCA P17252 2/20 0.30
ACACB O00763 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27781433 0.84 TSHR (0.43) ALDH1A1TSHRLMNAHSD17B10TDP1
SCHEMBL11428709 0.83 TDP1 (0.47) ALDH1A1TSHRLMNAHSD17B10TDP1
SCHEMBL4070149 0.83 TSHR (0.39) ALDH1A1TSHRLMNAHSD17B10TDP1
SCHEMBL8493145 0.82 ALDH1A1 (0.32) ALDH1A1TSHRLMNAHSD17B10TDP1
SCHEMBL27771526 0.81 THRB (0.42) ALDH1A1TSHR
SCHEMBL7709890 0.80 ALDH1A1 (0.40) ALDH1A1TSHRLMNAHSD17B10TDP1
SCHEMBL9810935 0.80 TSHR (0.40) ALDH1A1TSHRLMNATDP1CHRM2
SCHEMBL202380 0.80 ALDH1A1 (0.40) ALDH1A1TSHRLMNAHSD17B10TDP1
SCHEMBL2802408 0.80 ALDH1A1 (0.42) ALDH1A1TSHRPRKCA
SCHEMBL4400024 0.79 ALDH1A1 (0.32) ALDH1A1TSHRLMNAHSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6207130-B1 REACTING A CARBOXYLATO-ALUMOXANE (MONOCARBOXYLIC ACID LIGANDS) WITH A METAL ACETOACETONATE SOLUBILIZED OR DISPERSED IN A SOLVENT; ISOLATING AND CALCINING; GARNETS, SPINELS; HEAT AND CHEMICAL RESISTANCE RICE UNIVERSITY 2001-03-27 US claimed
US-9067845-B2 Process for hydrochlorination of multihydroxylated aliphatic hydrocarbons DOW GLOBAL TECHNOLOGIES LLC (US) 2015-06-30 US disclosed
EP-2047061-B1 A COMPOSITION AND METHOD FOR MAKING A PROPPANT OXANE MATERIALS INC (US) 2014-03-05 EP disclosed
US-8603578-B2 Composition and method for making a proppant OXANE MATERIALS, INC. (US) 2013-12-10 US disclosed
CN-103262305-A Surface protective agent composition for battery electrode or separator, battery electrode or separator protected by same, and battery having same KYORITSU CHEMICAL CO LTD 2013-08-21 CN disclosed
EP-2576489-A1 PROCESS FOR HYDROCHLORINATION OF MULTIHYDROXYLATED ALIPHATIC HYDROCARBONS Dow Global Technologies LLC (US) 2013-04-10 EP disclosed
US-20130066091-A1 PROCESS FOR HYDROCHLORINATION OF MULTIHYDROXYLATED ALIPHATIC HYDROCARBONS DOW GLOBAL TECHNOLOGIES LLC (US) 2013-03-14 US disclosed
US-20130022816-A1 Composition And Method For Making A Proppant OXANE MATERIALS, INC. (US) 2013-01-24 US disclosed
US-8298667-B2 Composition and method for making a proppant Oxane Materials (US) 2012-10-30 US disclosed
US-8075997-B2 Composition and method for making a proppant OXANE MATERIALS, INC. (US) 2011-12-13 US disclosed
EP-2047061-A2 A COMPOSITION AND METHOD FOR MAKING A PROPPANT Oxane Materials, Inc. (US) 2009-04-15 EP disclosed
US-7491444-B2 Composition and method for making a proppant OXANE MATERIALS, INC. (US) 2009-02-17 US disclosed
WO-2009012455-A1 PROPPANTS WITH CARBIDE AND/OR NITRIDE PHASES OXANE MATERIALS, INC. (US) 2009-01-22 WO disclosed
WO-2008018966-A2 A COMPOSITION AND METHOD FOR MAKING A PROPPANT OXANE MATERIALS, INC. (US) 2008-02-14 WO disclosed
US-20070202318-A1 Composition and method for making a proppant HALLIBURTON ENERGY SERVICES, INC. 2007-08-30 US disclosed
US-20070166541-A1 Composition and method for making a proppant HALLIBURTON ENERGY SERVICES, INC. 2007-07-19 US disclosed
US-6936306-B1 Chemical control over ceramic porosity using carboxylate-alumoxanes WILLIAM MARSH RICE UNIVERSITY (US) 2005-08-30 US disclosed
EP-1319639-A2 Chemical control over ceramic porosity using carboxylate-alumoxanes William Marsh Rice University (US) 2003-06-18 EP disclosed
EP-1070029-A1 CHEMICAL CONTROL OVER CERAMIC POROSITY USING CARBOXYLATE-ALUMOXANES William Marsh Rice University (US) 2001-01-24 EP disclosed
WO-1999050203-A1 CHEMICAL CONTROL OVER CERAMIC POROSITY USING CARBOXYLATE-ALUMOXANES WM MARSH RICE UNIVERSITY (US) 1999-10-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130066091-A1 PROCESS FOR HYDROCHLORINATION OF MULTIHYDROXYLATED ALIPHATIC HYDROCARBONS HDHD5, HRH3, HRH1 ALDH1A1 1034/4885TSHR 3287/4885LMNA 3941/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.