Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16075552 | 0.80 | MAPT (0.41) | SMN1; SMN2MAPTALDH1A1POLBKMT2A | |
| SCHEMBL17486664 | 0.79 | MAPT (0.40) | SMN1; SMN2MAPTALDH1A1POLBKMT2A | |
| SCHEMBL20392801 | 0.78 | L3MBTL1 (0.41) | SMN1; SMN2MAPTALDH1A1POLBMEN1 | |
| SCHEMBL16119715 | 0.78 | TSHR (0.42) | SMN1; SMN2MAPTALDH1A1POLBKMT2A | |
| SCHEMBL25595744 | 0.76 | SMN1; SMN2 (0.62) | SMN1; SMN2ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL18475748 | 0.76 | HCAR2 (0.38) | SMN1; SMN2MAPTALDH1A1POLBMEN1 | |
| SCHEMBL28287659 | 0.73 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1POLBL3MBTL1TSHR | |
| SCHEMBL8214792 | 0.72 | ALDH1A1 (0.36) | SMN1; SMN2MAPTALDH1A1POLBMEN1 | |
| SCHEMBL18775073 | 0.70 | ALDH1A1 (0.36) | SMN1; SMN2MAPTALDH1A1POLBMEN1 | |
| SCHEMBL7807640 | 0.69 | KMT2A (0.42) | MAPTALDH1A1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104755459-A | Fluoromethyl-substituted pyrrolecarboxamides | GRUENENTHAL CHEMIE | 2015-07-01 | — | — | CN | disclosed |