Quinoline

Quinoline

SCHEMBL28024422

CCCCc1ccc(-n2nc(C=Cc3ccccc3)cc2-c2ccccc2)cc1.c1ccc2ncccc2c1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CNR1 P21554 1/20 0.42
▸ CNR2 P34972 1/20 0.42
▸ ALOX5 P09917 1/20 0.41
▸ PDPK1 O15530 2/20 0.38
▸ MAPKAPK2 P49137 1/20 0.36
▸ KAT2B Q92831 2/20 0.36
▸ EP300 Q09472 1/20 0.36
▸ KAT2A Q92830 1/20 0.36
▸ PDGFRB P09619 1/20 0.36
▸ PDGFRA P16234 1/20 0.36
▸ PDE10A Q9Y233 1/20 0.35
▸ HSD11B1 P28845 1/20 0.35
▸ TRPV1 Q8NER1 1/20 0.35
▸ PSMB5 P28074 1/20 0.34
▸ DHODH Q02127 1/20 0.34
▸ MET P08581 1/20 0.34
▸ SLC5A1 P13866 5/20 0.34
▸ KDM4E B2RXH2 1/20 0.34
▸ NPC1 O15118 1/20 0.34
▸ LMNA P02545 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quinoline SCHEMBL27671669 0.96 CNR1 (0.45) CNR1CNR2ALOX5PDPK1MAPKAPK2
Quinoline SCHEMBL28771536 0.86 RAB9A (0.43) CNR1CNR2PDGFRBPDGFRAPDE10A
Quinoline SCHEMBL27651466 0.85 CNR1 (0.37) CNR1CNR2KDM4ENPC1RAB9A
Quinoline SCHEMBL28172017 0.84 CNR1 (0.46) CNR1CNR2ALOX5PDPK1KAT2B
Quinoline SCHEMBL27722665 0.83 RPA1 (0.47) PDE10AKDM4ENPC1LMNAPKM
Quinoline SCHEMBL27702294 0.83 FABP3 (0.40) ALOX5PDGFRBPDGFRAPDE10AMET
Quinoline SCHEMBL27722669 0.83 FABP3 (0.40) PDPK1PDGFRBPDGFRAPDE10ATRPV1
Quinoline SCHEMBL28111528 0.81 RAB9A (0.35) ALOX5PDGFRBPDGFRAPDE10ATRPV1
Quinoline SCHEMBL27671763 0.79 RAB9A (0.35) PDGFRBPDGFRAPDE10ATRPV1MET
Quinoline SCHEMBL27651469 0.79 RAB9A (0.36) PDGFRBPDGFRAPDE10ATRPV1MET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105793778-A PHOTOSENSITIVE RESIN COMPOSITION AND PHOTOSENSITIVE RESIN LAMINATE 旭化成株式会社 2016-07-20 — — CN disclosed
CN-102375341-B The manufacture method of photosensitive polymer combination, element, resist figure and lead frame, printed-wiring board (PWB) and manufacture method thereof HITACHI CHEMICAL CO., LTD. (JP) 2016-04-06 — — CN disclosed
CN-105431778-A Photosensitive resin composition HITACHI CHEMICAL CO LTD 2016-03-23 — — CN disclosed
CN-102662306-B The manufacture method of photosensitive element, corrosion-resisting pattern formation method and printed circuit board (PCB) HITACHI CHEMICAL CO., LTD. (JP) 2015-11-25 — — CN disclosed
CN-104808444-A Photosensitive resin composition, and photosensitive element, resist pattern formation method and printed circuit board production method each utilizing same HITACHI CHEMICAL CO LTD 2015-07-29 — — CN disclosed
Send feedback