Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.54 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.44 |
| ▸ | TUBB | P07437 | 4/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.44 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.44 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.44 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28025008 | 0.90 | ALOX5 (0.56) | ALOX5NR4A2KDM4EALDH1A1HPGD | |
| SCHEMBL28024558 | 0.85 | NR4A2 (0.48) | NR4A2KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL28206988 | 0.84 | MAP2 (0.45) | KDM4EHPGDMAPTRXFP1MEN1 | |
| SCHEMBL28024568 | 0.81 | NR4A2 (0.60) | ALOX5NR4A2KDM4EALDH1A1HPGD | |
| SCHEMBL28025009 | 0.79 | NR4A2 (0.50) | ALOX5NR4A2RAB9A | |
| SCHEMBL5234954 | 0.78 | NR4A2 (0.63) | ALOX5NR4A2KDM4EALDH1A1HPGD | |
| SCHEMBL28025011 | 0.78 | NR4A2 (0.46) | NR4A2KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL28024557 | 0.75 | NR4A2 (0.49) | NR4A2KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL31312633 | 0.74 | ALOX5 (0.57) | ALOX5NR4A2TUBB4ATUBBTUBA3C | |
| SCHEMBL19322278 | 0.74 | NR4A2 (0.50) | NR4A2KDM4EALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105646327-A | 2-perfluoroalkyl indole derivative and synthesis method thereof | 上海大学 | 2016-06-08 | — | — | CN | disclosed |
| CN-104892485-A | 2-perfluoroalkyl indole derivative and synthesis method thereof | UNIV SHANGHAI | 2015-09-09 | — | — | CN | disclosed |