Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.46 |
| ▸ | TUBB | P07437 | 3/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28025011 | 0.93 | NR4A2 (0.46) | NR4A2ALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL19322278 | 0.90 | NR4A2 (0.50) | NR4A2ALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL28206979 | 0.88 | ALDH1A1 (0.51) | ALDH1A1KDM4EHSD17B10MAPTMEN1 | |
| SCHEMBL28024554 | 0.85 | ALOX5 (0.54) | NR4A2ALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL28024568 | 0.81 | NR4A2 (0.60) | NR4A2ALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL28206983 | 0.81 | ALDH1A1 (0.49) | ALDH1A1KDM4EHSD17B10MAPTMEN1 | |
| SCHEMBL28025014 | 0.81 | KDM4E (0.51) | NR4A2KDM4EMAPTMEN1KMT2A | |
| SCHEMBL19322108 | 0.79 | ALDH1A1 (0.49) | ALDH1A1KDM4EHSD17B10MAPTMEN1 | |
| SCHEMBL28024553 | 0.79 | KDM4E (0.54) | NR4A2ALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL18919114 | 0.78 | ALDH1A1 (0.65) | NR4A2ALDH1A1KDM4EHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105646327-A | 2-perfluoroalkyl indole derivative and synthesis method thereof | 上海大学 | 2016-06-08 | — | — | CN | disclosed |
| CN-104892485-A | 2-perfluoroalkyl indole derivative and synthesis method thereof | UNIV SHANGHAI | 2015-09-09 | — | — | CN | disclosed |