Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.44 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28025008 | 0.89 | ALOX5 (0.56) | NR4A2RAB9AALOX5 | |
| SCHEMBL28024553 | 0.84 | KDM4E (0.54) | NR4A2ALOX15RAB9A | |
| SCHEMBL28207427 | 0.83 | KDM4E (0.50) | ALOX15 | |
| SCHEMBL28024552 | 0.83 | KIF11 (0.49) | NR4A2ALOX15RAB9A | |
| SCHEMBL28024559 | 0.83 | RAB9A (0.52) | NR4A2RAB9A | |
| SCHEMBL28207450 | 0.83 | RAB9A (0.52) | RAB9A | |
| SCHEMBL2082214 | 0.80 | NR4A2 (0.63) | NR4A2ALOX15ALOX5MAP2K4 | |
| SCHEMBL20867843 | 0.80 | NR4A2 (0.63) | NR4A2ALOX5 | |
| SCHEMBL28024566 | 0.80 | KIF11 (0.46) | RAB9A | |
| SCHEMBL28024554 | 0.79 | ALOX5 (0.54) | NR4A2RAB9AALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105646327-A | 2-perfluoroalkyl indole derivative and synthesis method thereof | 上海大学 | 2016-06-08 | — | — | CN | disclosed |
| CN-104892485-A | 2-perfluoroalkyl indole derivative and synthesis method thereof | UNIV SHANGHAI | 2015-09-09 | — | — | CN | disclosed |