SCHEMBL28024920

SCHEMBL28024920

CCCC(=O)c1c(C(N)=O)ccc(N)c1N

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.38
HSD17B3 P37058 1/20 0.37
HPGD P15428 2/20 0.36
ALDH1A1 P00352 1/20 0.36
ALOX15 P16050 1/20 0.36
TSHR P16473 1/20 0.36
RECQL P46063 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
STS P08842 1/20 0.33
IKBKB O14920 1/20 0.33
NOS2 P35228 1/20 0.33
MEN1 O00255 1/20 0.33
NR1I2 O75469 1/20 0.33
LMNA P02545 1/20 0.33
CHRM2 P08172 1/20 0.33
CYP3A4 P08684 1/20 0.33
ADRA2A P08913 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22123486 0.80 ALDH1A1 (0.40) PARP1HSD17B3HPGDALDH1A1HSD17B10
SCHEMBL28429668 0.76 ALDH1A1 (0.42) PARP1HSD17B3HPGDALDH1A1ALOX15
SCHEMBL28466149 0.73 HPGD (0.40) PARP1HSD17B3HPGDALDH1A1ALOX15
SCHEMBL28494378 0.72 ALDH1A1 (0.42) PARP1HSD17B3HPGDALDH1A1ALOX15
SCHEMBL22123487 0.72 ALDH1A1 (0.42) PARP1HSD17B3HPGDALDH1A1ALOX15
SCHEMBL27570581 0.72 HTT (0.57) HSD17B3ALDH1A1STSMEN1NR1I2
SCHEMBL6699177 0.72 FASN (0.41) HSD17B3HPGDALDH1A1RECQLTDP1
SCHEMBL11071972 0.70 TSHR (0.43) HSD17B3HPGDALDH1A1ALOX15TSHR
SCHEMBL9631839 0.70 ALDH1A1 (0.43) HSD17B3HPGDALDH1A1ALOX15TSHR
SCHEMBL17868830 0.70 HTT (0.40) HSD17B3ALDH1A1STSMEN1NR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112353746-A Skin care composition with skin cell regeneration activating effect and face tightening and lifting anti-aging effect and using method 江苏美之龄商务发展有限公司 2021-02-12 CN claimed
CN-112641656-A Polypeptide microneedle and preparation method thereof 宇肽生物(东莞)有限公司 2021-04-13 CN disclosed
CN-112587433-A Polypeptide freeze-dried tablet and preparation method thereof 宇肽生物(东莞)有限公司 2021-04-02 CN disclosed
CN-112353746-A Skin care composition with skin cell regeneration activating effect and face tightening and lifting anti-aging effect and using method 江苏美之龄商务发展有限公司 2021-02-12 CN disclosed
CN-111110584-A Skin care composition with moisturizing and anti-aging effects and preparation method thereof 广东博然堂生物科技有限公司 2020-05-08 CN disclosed
CN-104784092-A Nutrient solution for instantly repairing skin SHENYANG YIFEILIN BIOTECHNOLOGY CO LTD 2015-07-22 CN disclosed