Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 13/20 | 0.68 |
| ▸ | GABRG2 | P18507 | 13/20 | 0.68 |
| ▸ | GABRB3 | P28472 | 13/20 | 0.68 |
| ▸ | GABRA5 | P31644 | 13/20 | 0.68 |
| ▸ | GABRA3 | P34903 | 13/20 | 0.68 |
| ▸ | GABRA2 | P47869 | 13/20 | 0.68 |
| ▸ | GABRA6 | Q16445 | 13/20 | 0.68 |
| ▸ | GABRP | O00591 | 12/20 | 0.68 |
| ▸ | GABRD | O14764 | 12/20 | 0.68 |
| ▸ | GABRB1 | P18505 | 12/20 | 0.68 |
| ▸ | GABRB2 | P47870 | 12/20 | 0.68 |
| ▸ | GABRA4 | P48169 | 12/20 | 0.68 |
| ▸ | GABRE | P78334 | 12/20 | 0.68 |
| ▸ | GABRG1 | Q8N1C3 | 12/20 | 0.68 |
| ▸ | GABRG3 | Q99928 | 12/20 | 0.68 |
| ▸ | GABRQ | Q9UN88 | 12/20 | 0.68 |
| ▸ | CHUK | O15111 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL406255 | 0.82 | CHUK (0.62) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL10646617 | 0.81 | GABRA1 (1.00) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL1427646 | 0.80 | CHEK1 (0.58) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL14689472 | 0.79 | CHUK (0.58) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL29366993 | 0.75 | CHUK (0.64) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL38602 | 0.75 | CHUK (0.64) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL1980977 | 0.75 | ALDH1A1 (0.66) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL6976263 | 0.75 | ALDH1A1 (0.78) | CHUKKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL31188764 | 0.75 | ALDH1A1 (0.78) | CHUKKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL10646757 | 0.74 | GABRA1 (0.89) | GABRA1GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104754941-A | Proneurogenic compounds | UNIV TEXAS | 2015-07-01 | — | — | CN | claimed |
| CN-104754941-A | Proneurogenic compounds | UNIV TEXAS | 2015-07-01 | — | — | CN | disclosed |