Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 4/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27604020 | 0.83 | AIMP2 (0.44) | MAOADRD4SIGMAR1AIMP2HDAC1 | |
| SCHEMBL31497405 | 0.79 | GRIN1 (0.48) | KDM1AMAOAMAOBKDM4EMAPT | |
| SCHEMBL2754953 | 0.78 | ALDH1A1 (0.39) | DRD4AIMP2MAPTCYP2A6 | |
| SCHEMBL1673434 | 0.76 | CYP1A2 (0.34) | DRD4AIMP2CYP2A6 | |
| SCHEMBL7810045 | 0.75 | HTR1D (0.54) | KDM1AMAOAMAOBAIMP2KDM4E | |
| SCHEMBL7813934 | 0.75 | HTR1D (0.54) | KDM1AMAOAMAOBAIMP2KDM4E | |
| SCHEMBL7810050 | 0.75 | HTR1D (0.54) | KDM1AMAOAMAOBAIMP2KDM4E | |
| Water SCHEMBL5596576 | 0.74 | ACHE (0.33) | DRD4AIMP2CYP2A6 | |
| SCHEMBL8666600 | 0.74 | HDAC1 (0.55) | KDM1AMAOAMAOBMAPTAHR | |
| SCHEMBL27925000 | 0.74 | KMT2A (0.44) | KDM4EMAPTAHRUSP2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104754941-B | Proneurogenic compounds | 得克萨斯州大学系统董事会 | 2018-02-27 | — | — | CN | disclosed |
| CN-107595841-A | Preceding neurogenic compounds | 得克萨斯州大学系统董事会 | 2018-01-19 | — | — | CN | disclosed |
| CN-104754941-A | Proneurogenic compounds | UNIV TEXAS | 2015-07-01 | — | — | CN | disclosed |