Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 1/20 | 0.48 |
| ▸ | CCR3 | P51677 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | AHR | P35869 | 4/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | F3 | P13726 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28024995 | 0.79 | KDM1A (0.44) | KDM1AMAOAMAOBAHRNR4A2 | |
| SCHEMBL8666600 | 0.77 | HDAC1 (0.55) | KDM1AMAOAMAOBAHRNR4A2 | |
| SCHEMBL18917988 | 0.76 | ALDH1A1 (0.62) | GRIN1CCR3GAAMAPT | |
| SCHEMBL20847613 | 0.75 | KDM1A (0.59) | KDM1AMAOAMAOBMAPTSLC6A2 | |
| SCHEMBL5057022 | 0.73 | AHR (0.50) | KDM1AMAOAMAOBAHRNR4A2 | |
| SCHEMBL6582346 | 0.73 | AHR (0.55) | KDM1AMAOAMAOBAHRNR4A2 | |
| SCHEMBL763201 | 0.73 | AHR (0.50) | KDM1AMAOAMAOBAHRNR4A2 | |
| SCHEMBL17613377 | 0.73 | AHR (0.50) | KDM1AMAOAMAOBAHRNR4A2 | |
| SCHEMBL6963327 | 0.73 | AHR (0.50) | KDM1AMAOAMAOBAHRNR4A2 | |
| SCHEMBL951685 | 0.73 | USP2 (0.55) | KDM1AMAOAMAOBAHRNR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119490487-A | Polysubstituted tetrahydrocarbazole compound, preparation method, pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2025-02-21 | — | — | CN | disclosed |