Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 5/20 | 0.42 |
| ▸ | CHRM2 known ✓ | P08172 | 4/20 | 0.42 |
| ▸ | CHRM3 known ✓ | P20309 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | GALR3 | O60755 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.36 |
| ▸ | CPT2 | P23786 | 1/20 | 0.34 |
| ▸ | CPT1A | P50416 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL7979734 | 0.86 | MAPT (0.47) | LMNAMAPTCHRM1CHRM2CHRM4 | |
| Methacrylic Acid SCHEMBL27466382 | 0.83 | MAPT (0.43) | LMNAMAPTCHRM1CHRM2CHRM4 | |
| Methacrylic Acid SCHEMBL25248517 | 0.82 | MAPT (0.42) | LMNAMAPTCHRM1CHRM2CHRM4 | |
| Methacrylic Acid SCHEMBL6678142 | 0.82 | SLC22A16 (0.47) | LMNAMAPTCHRM1CHRM2CHRM4 | |
| Carbamic Acid SCHEMBL11505008 | 0.81 | MAPT (0.50) | LMNAMAPTCHRM1CHRM2CHRM4 | |
| Acrylamide SCHEMBL27953686 | 0.80 | MAPT (0.46) | LMNAMAPTCHRM1CHRM2CHRM4 | |
| Methacrylic Acid SCHEMBL29064100 | 0.80 | SLC22A16 (0.45) | LMNAMAPTCHRM1CHRM2CHRM4 | |
| Acetic Acid SCHEMBL11505398 | 0.79 | SLC22A16 (0.52) | LMNAMAPTCHRM1CHRM2CHRM4 | |
| Acetic Acid SCHEMBL28210362 | 0.78 | MAPT (0.50) | LMNAMAPTCHRM1CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL9748760 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109679036-A | The preparation method and cationic high-molecular flocculant of a kind of cationic high-molecular polymer and its application | 厦门大学 | 2019-04-26 | — | — | CN | claimed |
| CN-107353760-A | Polyacrylamide coating with super-hydrophilic property and preparation method and application thereof | 中国科学院理化技术研究所 | 2017-11-17 | — | — | CN | claimed |
| CN-104909399-A | Ultra-pure cerium oxide sol | ANHUI JIANGNAN JINGSHENG NEW MATERIALS CO LTD | 2015-09-16 | — | — | CN | claimed |
| CN-109679036-A | The preparation method and cationic high-molecular flocculant of a kind of cationic high-molecular polymer and its application | 厦门大学 | 2019-04-26 | — | — | CN | disclosed |
| CN-107353760-A | Polyacrylamide coating with super-hydrophilic property and preparation method and application thereof | 中国科学院理化技术研究所 | 2017-11-17 | — | — | CN | disclosed |
| CN-104909399-B | A kind of ultrapure cerium oxygen compound colloidal sol | 安徽江南晶盛新材料有限公司 | 2016-08-17 | — | — | CN | disclosed |
| CN-104909399-A | Ultra-pure cerium oxide sol | ANHUI JIANGNAN JINGSHENG NEW MATERIALS CO LTD | 2015-09-16 | — | — | CN | disclosed |