Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | C1S | P09871 | 1/20 | 0.53 |
| ▸ | EIF4E | P06730 | 8/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | USP8 | P40818 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5968562 | 0.81 | RAB9A (0.62) | GFERKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL6018315 | 0.80 | BCAT2 (0.56) | KDM4EALDH1A1 | |
| SCHEMBL28355353 | 0.75 | KDM4E (0.68) | KDM4EMEN1KMT2AALDH1A1EIF4E | |
| SCHEMBL21462074 | 0.75 | KDM4E (0.68) | KDM4EMEN1KMT2AALDH1A1EIF4E | |
| SCHEMBL28662231 | 0.75 | BCAT2 (0.56) | KDM4EALDH1A1 | |
| SCHEMBL27965806 | 0.74 | RAB9A (0.78) | GFERKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL21479755 | 0.74 | SMN1; SMN2 (0.65) | GFERKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL30279818 | 0.74 | SMN1; SMN2 (0.65) | GFERKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL22617059 | 0.73 | USP2 (0.66) | KDM4EMEN1KMT2AUSP2USP8 | |
| SCHEMBL7221341 | 0.72 | KDM4E (0.74) | GFERKDM4EMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103232406-B | A kind of 1,3-thiazoles derivative | PEKING UNIVERSITY (CN) | 2015-07-29 | — | — | CN | disclosed |