Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.68 |
| ▸ | AR | P10275 | 2/20 | 0.68 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | LTA4H | P09960 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21462074 | 1.00 | KDM4E (0.68) | KDM4EKMT2AARSREBF2MEN1 | |
| SCHEMBL21479710 | 0.93 | KDM4E (0.68) | KDM4EKMT2AARSREBF2MEN1 | |
| SCHEMBL27810026 | 0.92 | KMT2A (0.57) | KDM4EKMT2AARSREBF2MEN1 | |
| SCHEMBL21479644 | 0.86 | KMT2A (0.67) | KDM4EKMT2AARSREBF2MEN1 | |
| SCHEMBL30279814 | 0.86 | KMT2A (0.67) | KDM4EKMT2AARSREBF2MEN1 | |
| SCHEMBL11212983 | 0.86 | SREBF2 (0.82) | KDM4EKMT2AARSREBF2MEN1 | |
| SCHEMBL11213828 | 0.86 | SREBF2 (0.82) | KDM4EKMT2AARSREBF2MEN1 | |
| SCHEMBL11215130 | 0.86 | SREBF2 (0.82) | KDM4EKMT2AARSREBF2MEN1 | |
| SCHEMBL28708805 | 0.86 | LTA4H (0.62) | KDM4EKMT2AARSREBF2MEN1 | |
| SCHEMBL15160564 | 0.86 | KDM4E (0.71) | KDM4EKMT2AARSREBF2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250270199-A1 | THIAZOLE DERIVATIVES AND METHODS OF USING THE SAME | ARKANSAS STATE UNIV JONESBORO (US) | 2025-08-28 | — | — | US | disclosed |
| CN-110627739-B | Method for synthesizing thiazole heterocyclic compound through photocatalysis | 桂林医学院 | 2023-02-07 | — | — | CN | disclosed |
| CN-110627739-A | Method for synthesizing thiazole heterocyclic compound through photocatalysis | 桂林医学院 | 2019-12-31 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250270199-A1 | THIAZOLE DERIVATIVES AND METHODS OF USING THE SAME | TST, GOT2, TPMT | KDM4E 4630/4885KMT2A 3923/4885AR 3042/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.