Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8169595 | 0.98 | TSHR (0.38) | TSHRTNKSTNKS2PARP3MAPT | |
| SCHEMBL27460809 | 0.84 | HTR2A (0.40) | LMNAHTR6HTR2A | |
| SCHEMBL2830664 | 0.80 | PRCP (0.39) | TSHRTNKS2MAPTTDP1LMNA | |
| SCHEMBL9145143 | 0.80 | HTR2A (0.38) | LMNAHTR6HTR2AALDH1A1 | |
| SCHEMBL28385224 | 0.79 | KIF11 (0.37) | MAPTTDP1L3MBTL1KDM1ANPC1 | |
| SCHEMBL1028466 | 0.78 | HTR2A (0.39) | LMNAHTR6HTR2AALDH1A1 | |
| SCHEMBL17835299 | 0.78 | ALDH1A1 (0.36) | TSHRTDP1L3MBTL1LMNAHDAC2 | |
| SCHEMBL30355050 | 0.78 | ALDH1A1 (0.36) | TSHRTDP1L3MBTL1LMNAHDAC2 | |
| SCHEMBL9145856 | 0.76 | HTR2A (0.38) | LMNAHTR6HTR2AALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL21245914 | 0.76 | HTR2A (0.38) | LMNAHTR6HTR2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104822697-A | Bridged metallocene compounds, catalyst systems and polymerization processes using the same | EXXONMOBIL CHEM PATENTS INC | 2015-08-05 | — | — | CN | disclosed |