Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6768193 | 0.80 | ELANE (0.43) | ELANEKDM4EALDH1A1HPGDGAA | |
| SCHEMBL3921968 | 0.78 | CYP1A2 (0.60) | KDM4EALDH1A1HPGDSMN1; SMN2TDP1 | |
| SCHEMBL11341944 | 0.78 | ELANE (0.42) | ELANEKDM4EALDH1A1HPGDGAA | |
| SCHEMBL832390 | 0.78 | MAOA (0.47) | ELANEKDM4EALDH1A1HPGDGAA | |
| SCHEMBL6629242 | 0.78 | POLB (0.47) | ELANEKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3403322 | 0.78 | ELANE (0.39) | ELANEKDM4EALDH1A1HPGDGAA | |
| SCHEMBL6631411 | 0.77 | ACHE (0.58) | KDM4EHPGDSMN1; SMN2ACHELMNA | |
| SCHEMBL1257332 | 0.77 | BACE1 (0.44) | ELANEKDM4EALDH1A1HPGDGAA | |
| SCHEMBL29726892 | 0.77 | BACE1 (0.44) | ELANEKDM4EALDH1A1HPGDGAA | |
| SCHEMBL28236229 | 0.74 | ELANE (0.42) | ELANEKDM4EALDH1A1HPGDMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105218588-A | A kind of preparation method and application of pyridyl benzoglyoxaline phenylquinoline iridium (III) title complex based on Long carbon chain modification | UNIV NANJING POSTS & TELECOMM | 2016-01-06 | — | — | CN | claimed |
| CN-104910213-A | Phenyl quinoline derivative iridium (III) complex based on piperidine or morpholine methylene substitution, and preparation method and application thereof | UNIV NANJING POSTS & TELECOMM | 2015-09-16 | — | — | CN | claimed |
| CN-104910213-B | A kind of phenylchinoline derivative iridium (III) complex substituted based on piperidines or morpholine methylene and its preparation method and application | 南京邮电大学 | 2018-05-18 | — | — | CN | disclosed |
| CN-105218588-A | A kind of preparation method and application of pyridyl benzoglyoxaline phenylquinoline iridium (III) title complex based on Long carbon chain modification | UNIV NANJING POSTS & TELECOMM | 2016-01-06 | — | — | CN | disclosed |
| CN-104910213-A | Phenyl quinoline derivative iridium (III) complex based on piperidine or morpholine methylene substitution, and preparation method and application thereof | UNIV NANJING POSTS & TELECOMM | 2015-09-16 | — | — | CN | disclosed |
| CN-103254243-A | Polysubstituted phenylquinoline iridium (III) complex, preparation method thereof and application | UNIV TAIYUAN TECHNOLOGY | 2013-08-21 | — | — | CN | disclosed |
| CN-103254242-A | Polysubstituted phenylquinoline platinum (II) complex as well as preparation method and application thereof | UNIV TAIYUAN TECHNOLOGY | 2013-08-21 | — | — | CN | disclosed |