SCHEMBL28025944

SCHEMBL28025944

CC1=C(c2ccccc2)c2c(C)c(C)c(C)c(C)c2[CH]1

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PDE4B Q07343 1/20 0.35
PTGS2 P35354 2/20 0.34
MAPT P10636 3/20 0.33
HTT P42858 2/20 0.33
LMNA P02545 1/20 0.33
ALDH1A1 P00352 2/20 0.32
MITF O75030 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
CDC25A P30304 1/20 0.31
CDC25B P30305 1/20 0.31
KMT2A Q03164 1/20 0.31
HK2 P52789 1/20 0.30
MAOB P27338 1/20 0.30
HSP90AA1 P07900 1/20 0.30
HSP90AB1 P08238 1/20 0.30
PDGFRA P16234 1/20 0.30
MAPK8 P45983 1/20 0.30
CDK5 Q00535 1/20 0.30
CLK4 Q9HAZ1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28521499 0.76 FGFR1 (0.36) PDE4BPTGS2MAPTHTTLMNA
SCHEMBL28460097 0.73 PDE4B (0.46) PDE4BPTGS2MAPTHTTLMNA
SCHEMBL6294085 0.70 LMNA (0.48) PDE4BPTGS2MAPTHTTLMNA
SCHEMBL8618279 0.70 LMNA (0.48) PDE4BPTGS2MAPTHTTLMNA
SCHEMBL9701681 0.68 LMNA (0.46) PDE4BPTGS2MAPTHTTLMNA
SCHEMBL9701635 0.67 LMNA (0.50) PDE4BPTGS2MAPTHTTLMNA
SCHEMBL28025533 0.67 FGFR1 (0.41) PDE4BPTGS2MAPTHTTLMNA
SCHEMBL366869 0.66
SCHEMBL27619559 0.65 LMNA (0.48) PDE4BPTGS2MAPTHTTLMNA
SCHEMBL2864343 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108137729-B Catalysts for forming multimodal polymers 埃克森美孚化学专利公司 2021-02-05 CN disclosed
CN-104822697-A Bridged metallocene compounds, catalyst systems and polymerization processes using the same EXXONMOBIL CHEM PATENTS INC 2015-08-05 CN disclosed