SCHEMBL28025533

SCHEMBL28025533

CC1=C(c2ccccc2)c2c(C)cccc2[CH]1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 1/20 0.41
FGFR2 P21802 1/20 0.41
FGFR4 P22455 1/20 0.41
FGFR3 P22607 1/20 0.41
FABP4 P15090 2/20 0.38
ADORA3 P0DMS8 1/20 0.36
ADORA2A P29274 1/20 0.36
ADORA1 P30542 1/20 0.36
RET P07949 1/20 0.35
PDE4B Q07343 2/20 0.34
MYC P01106 1/20 0.34
TSHR P16473 2/20 0.33
ACHE P22303 2/20 0.33
KDM4E B2RXH2 1/20 0.33
PTGS2 P35354 1/20 0.33
MAPT P10636 2/20 0.33
TYMS P04818 1/20 0.33
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
LMNA P02545 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28520267 0.78 TP53 (0.36) ADORA3ADORA2AADORA1PDE4BKDM4E
SCHEMBL8154866 0.75 MAOA (0.39) TSHRKDM4EMAPTMAOAMAOB
SCHEMBL28521499 0.74 FGFR1 (0.36) FGFR1FGFR2FGFR4FGFR3FABP4
SCHEMBL28025979 0.74 ALDH1A1 (0.41) FGFR1FGFR2FGFR4FGFR3PDE4B
SCHEMBL2964933 0.73 FABP4 (0.35) FGFR1FGFR2FGFR4FGFR3FABP4
SCHEMBL218448 0.73 CYP2A6 (0.36) MYCTSHRACHE
SCHEMBL28460097 0.71 PDE4B (0.46) PDE4BTSHRACHEPTGS2MAPT
SCHEMBL2050326 0.71 CD44 (0.48) MYCTSHRACHE
SCHEMBL4426820 0.71 TSHR (0.50) FABP4MYCTSHRACHEMAPT
Benzoquinone SCHEMBL27494284 0.69 LMNA (0.46) FGFR1FGFR2FGFR4FGFR3FABP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108137729-B Catalysts for forming multimodal polymers 埃克森美孚化学专利公司 2021-02-05 CN disclosed
CN-104822697-A Bridged metallocene compounds, catalyst systems and polymerization processes using the same EXXONMOBIL CHEM PATENTS INC 2015-08-05 CN disclosed