SCHEMBL28025959

SCHEMBL28025959

Clc1cc(Cl)cc(C2=C[CH]c3ccccc32)c1

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 1/20 0.46
CNR2 P34972 4/20 0.34
CNR1 P21554 3/20 0.34
RXRA P19793 1/20 0.33
RXRB P28702 1/20 0.33
PDK2 Q15119 1/20 0.33
HSD11B1 P28845 1/20 0.32
TSHR P16473 1/20 0.31
CYP2A6 P11509 1/20 0.30
ADORA2A P29274 1/20 0.30
ADORA2B P29275 1/20 0.30
ADORA1 P30542 1/20 0.30
EDNRB P24530 1/20 0.30
EDNRA P25101 1/20 0.30
PTAFR P25105 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28025937 0.85 PTAFR (0.40) PDK2TSHRADORA2AADORA1PTAFR
SCHEMBL28025982 0.82 CYP1A2 (0.43) TSHRADORA2AADORA1PTAFR
SCHEMBL28025988 0.81 PDK2 (0.36) PTPRCPDK2CYP2A6ADORA2APTAFR
SCHEMBL28219408 0.78 ALDH1A1 (0.36) CYP2A6
SCHEMBL5076754 0.77 ALDH1A1 (0.41) PTPRCCYP2A6
SCHEMBL28025423 0.77 BRD9 (0.34) TSHRADORA2AADORA1
SCHEMBL28025517 0.77 CNR1 (0.33) CNR2CNR1CYP2A6
SCHEMBL5824297 0.76 MEN1 (0.32) PTPRC
SCHEMBL28302278 0.76 BRD9 (0.33) TSHR
SCHEMBL28303649 0.75 ALDH1A1 (0.39) PTPRCCYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109824802-A Metallocenic compound, catalyst system and the polymerization using them of bridging 埃克森美孚化学专利公司 2019-05-31 CN claimed
CN-108137729-B Catalysts for forming multimodal polymers 埃克森美孚化学专利公司 2021-02-05 CN disclosed
CN-109824802-A Metallocenic compound, catalyst system and the polymerization using them of bridging 埃克森美孚化学专利公司 2019-05-31 CN disclosed
CN-108137729-A It is used to form the catalyst of multimodal polymer 埃克森美孚化学专利公司 2018-06-08 CN disclosed
CN-104822697-A Bridged metallocene compounds, catalyst systems and polymerization processes using the same EXXONMOBIL CHEM PATENTS INC 2015-08-05 CN disclosed