SCHEMBL5076754

SCHEMBL5076754

[CH]1C=C(c2ccccc2)c2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.41
MAPK1 P28482 2/20 0.41
BACE1 P56817 5/20 0.38
PTPN1 P18031 2/20 0.38
PTPRC P08575 1/20 0.38
PTPRF P10586 1/20 0.38
CDC25B P30305 1/20 0.38
HSD17B10 Q99714 2/20 0.36
HPGD P15428 1/20 0.36
BCL2L1 Q07817 1/20 0.36
CYP2A6 P11509 1/20 0.36
DPP4 P27487 1/20 0.32
MAOB P27338 2/20 0.31
HDAC4 P56524 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
MAOA P21397 1/20 0.31
NISCH Q9Y2I1 1/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28303649 0.98 ALDH1A1 (0.39) ALDH1A1MAPK1BACE1PTPN1PTPRC
SCHEMBL27502471 0.92 ALDH1A1 (0.35) ALDH1A1MAPK1BACE1PTPN1PTPRC
SCHEMBL28219408 0.87 ALDH1A1 (0.36) ALDH1A1MAPK1BACE1PTPN1HSD17B10
SCHEMBL5824297 0.85 MEN1 (0.32) ALDH1A1MAPK1PTPN1PTPRCCDC25B
SCHEMBL28515419 0.85 NPC1 (0.39) ALDH1A1MAPK1HPGDTDP1
SCHEMBL28025966 0.83 PTGS2 (0.38) ALDH1A1MAOB
SCHEMBL28025982 0.83 CYP1A2 (0.43) ALDH1A1HSD17B10HPGDMAOB
SCHEMBL28515991 0.78 KIF11 (0.48) ALDH1A1BACE1HSD17B10MAOB
SCHEMBL28512208 0.78 RAB9A (0.39) ALDH1A1HSD17B10HPGDNISCH
SCHEMBL28025440 0.78 TP53 (0.40) ALDH1A1MAPK1CYP2A6TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114716585-B Catalyst system containing aryloxy side-arm metallocene fourth subgroup metal complex and application thereof 吉林大学 2023-02-28 CN claimed
CN-114716585-A Catalyst system containing aryloxy side-arm metallocene fourth subgroup metal complex and application thereof 吉林大学 2022-07-08 CN claimed
CN-109824802-A Metallocenic compound, catalyst system and the polymerization using them of bridging 埃克森美孚化学专利公司 2019-05-31 CN claimed
CN-1289554-C Polymerization process for producing copolymers of propylene BOREALIS POLYMERS OY (FI) 2006-12-13 CN claimed
CN-1537123-A polymerization process for producing propylene copolymers 2004-10-13 CN claimed
CN-111094223-B binaphthyl compounds 罗伊特化学仪器制造公司 2023-10-27 CN disclosed
CN-110650964-B Dihydrocarbyl-silyl-bridged-substituted cyclopentadienyl metallocene complexes for olefin polymerization SABIC环球技术有限责任公司 2023-09-12 CN disclosed
CN-114716585-B Catalyst system containing aryloxy side-arm metallocene fourth subgroup metal complex and application thereof 吉林大学 2023-02-28 CN disclosed
CN-111344316-B Polyethylene compositions and articles made therefrom 埃克森美孚化学专利公司 2023-02-03 CN disclosed
US-20230026039-A1 Machine Direction Oriented Polyethylene Films EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-01-26 US disclosed
CN-112154163-B Transition metal compound and method for preparing polypropylene using the same LG化学株式会社 2022-12-27 CN disclosed
CN-110650978-B Dimethyl-silyl-bridged-1-substituted-2-indenyl metallocene complexes for olefin polymerization SABIC环球技术有限责任公司 2022-09-23 CN disclosed
WO-2001083571-A2 CATALYSTS CONTAINING N-PYRROLYL SUBSTITUTED NITROGEN DONORS EASTMAN CHEMICAL COMPANY (US) 2001-11-08 WO disclosed
EP-0946574-A1 3-ARYL SUBSTITUTED INDENYL CONTAINING METAL COMPLEXES AND POLYMERIZATION PROCESS THE DOW CHEMICAL COMPANY (US) 1999-10-06 EP disclosed
US-5959047-A AN AROMATIC COMPLEX OF TITANIUM OR ZIRCONIUM OR HAFNIUM USED FOR POLYMERIZATION OF OLEFIN; THE DOW CHEMICAL COMPANY (US) 1999-09-28 US disclosed
US-5866704-A 3-aryl substituted indenyl containing metal complexes and polymerization process THE DOW CHEMICAL COMPANY (US) 1999-02-02 US disclosed
WO-1998027102-A1 3-ARYL SUBSTITUTED INDENYL CONTAINING METAL COMPLEXES AND POLYMERIZATION PROCESS THE DOW CHEMICAL COMPANY (US) 1998-06-25 WO disclosed
EP-0837887-A1 POLYMERIZATION OF CRYSTALLINE COPOLYMERS OF OLEFINS AND CYCLIC OLEFINS EXXON CHEMICAL PATENTS INC. (US) 1998-04-29 EP disclosed
US-5621054-A CONTACTING OLEFINS WITH ACTIVE POLYMERIZATION CATALYST COMPRISING HAFNIUM OR ZIRCONIUM COMPOUND CONTAINING ASYMMETRICALLY SUBSTITUTED CYCLOPENTADIENYL LIGAND COVALENTLY BRIDGED TO BULKY HETEROATOM LIGAND EXXON CHEMICAL PATENTS INC. (US) 1997-04-15 US disclosed
WO-1996040806-A1 POLYMERIZATION OF CRYSTALLINE COPOLYMERS OF OLEFINS AND CYCLIC OLEFINS EXXON CHEMICAL PATENTS INC. (US) 1996-12-19 WO disclosed