SCHEMBL28025517

SCHEMBL28025517

Fc1cc(F)cc(C2=C[CH]c3ccccc32)c1

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33
HTR1A P08908 1/20 0.32
CTDSP1 Q9GZU7 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2A6 P11509 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28025419 0.85 TAAR1 (0.39) HTR1A
SCHEMBL28025932 0.83 ALOX5AP (0.30)
SCHEMBL28025966 0.82 PTGS2 (0.38)
SCHEMBL28025446 0.79 TTR (0.33)
SCHEMBL28219408 0.78 ALDH1A1 (0.36) CYP2A6
SCHEMBL28025430 0.78 MAOB (0.39) CYP1A2
SCHEMBL5076754 0.77 ALDH1A1 (0.41) TDP1CYP2A6
SCHEMBL28025423 0.77 BRD9 (0.34) HTR1A
SCHEMBL28025959 0.77 PTPRC (0.46) CNR1CNR2CYP2A6
SCHEMBL17293164 0.77 CNR1 (0.38) CNR1CNR2HTR1ATDP1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109824802-A Metallocenic compound, catalyst system and the polymerization using them of bridging 埃克森美孚化学专利公司 2019-05-31 CN claimed
CN-108137729-B Catalysts for forming multimodal polymers 埃克森美孚化学专利公司 2021-02-05 CN disclosed
CN-109824802-A Metallocenic compound, catalyst system and the polymerization using them of bridging 埃克森美孚化学专利公司 2019-05-31 CN disclosed
CN-108137729-A It is used to form the catalyst of multimodal polymer 埃克森美孚化学专利公司 2018-06-08 CN disclosed
CN-104822697-A Bridged metallocene compounds, catalyst systems and polymerization processes using the same EXXONMOBIL CHEM PATENTS INC 2015-08-05 CN disclosed