SCHEMBL28026003

SCHEMBL28026003

CCCCOc1ccc(C2(O)CCC(=O)CC2)c(F)c1F

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
S1PR5 Q9H228 2/20 0.39
S1PR1 P21453 1/20 0.39
RXRA P19793 5/20 0.36
CA9 Q16790 1/20 0.34
CRBN Q96SW2 2/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33
HNF4A P41235 2/20 0.32
PPARG P37231 1/20 0.32
FAAH O00519 1/20 0.32
LMNA P02545 1/20 0.32
NPY1R P25929 1/20 0.32
NPY2R P49146 1/20 0.32
PPARA Q07869 1/20 0.32
SLC6A5 Q9Y345 1/20 0.32
THRB P10828 1/20 0.32
KCNA3 P22001 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1574521 0.85 S1PR5 (0.39) S1PR5S1PR1RXRACA9MEN1
SCHEMBL425880 0.80 S1PR5 (0.38) S1PR5S1PR1RXRACA9LMNA
SCHEMBL1243209 0.77 S1PR5 (0.34) S1PR5S1PR1RXRACRBNMEN1
SCHEMBL2931710 0.76 S1PR5 (0.34) S1PR5S1PR1PPARG
SCHEMBL426306 0.76 GPR119 (0.35) S1PR5S1PR1CA9
SCHEMBL421950 0.74 SCN9A (0.34) S1PR5S1PR1RXRAMEN1KMT2A
SCHEMBL15120786 0.73 CYP1A2 (0.50) CA9
SCHEMBL425191 0.71 SCN9A (0.40) CA9CRBNMEN1KMT2APPARG
SCHEMBL13323500 0.70 MEN1 (0.39) RXRAMEN1KMT2A
SCHEMBL24661358 0.70 CYP1A2 (0.47) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104844428-B A kind of preparation method of trienes liquid crystal monomer 中节能万润股份有限公司 2016-08-24 CN disclosed
CN-104844428-A Preparation method of trienes liquid crystal monomers VALIANT CO LTD 2015-08-19 CN disclosed