SCHEMBL425191

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2506385	0.95	PTPN1 (0.37)	SCN9APPARGLMNAKMT2AMAPT
	SCHEMBL429400	0.92	SCN9A (0.38)	SCN9APPARGPDE4APDE4DPDE4B
	SCHEMBL1243882	0.89	HCRTR2 (0.38)	PDE4APDE4DPDE4BPDE4CCRBN
	SCHEMBL14922527	0.89	SCN9A (0.42)	SCN9APDE4APDE4DPDE4BPDE4C
	SCHEMBL1242503	0.86	L3MBTL1 (0.41)	SCN9APDE4APDE4DPDE4BPDE4C
	SCHEMBL14922537	0.86	L3MBTL1 (0.41)	SCN9APDE4APDE4DPDE4BPDE4C
	SCHEMBL11917368	0.85	SCN9A (0.35)	SCN9AHRH3CRBNKMT2ACA9
	SCHEMBL2506935	0.84	HCRTR2 (0.36)	PDE4APDE4DPDE4BPDE4CCRBN
	SCHEMBL14371074	0.83	SCN9A (0.39)	SCN9APDE4APDE4DPDE4BPDE4C
	SCHEMBL12733630	0.83	SCN9A (0.39)	SCN9APDE4APDE4DPDE4BPDE4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.