Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3105876 | 0.85 | TBXAS1 (0.54) | TBXAS1SMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2437120 | 0.81 | FABP7 (0.38) | TBXAS1FFAR1 | |
| SCHEMBL7388461 | 0.81 | TBXAS1 (0.56) | TBXAS1 | |
| SCHEMBL28027156 | 0.81 | TBXAS1 (0.49) | TBXAS1SMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27969567 | 0.81 | TBXAS1 (0.49) | TBXAS1SMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11259709 | 0.81 | FFAR1 (0.52) | TBXAS1SMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11024053 | 0.81 | TBXAS1 (0.49) | TBXAS1SMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28027146 | 0.81 | TBXAS1 (0.49) | TBXAS1SMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14997657 | 0.81 | TBXAS1 (0.49) | TBXAS1SMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL535547 | 0.81 | TBXAS1 (0.49) | TBXAS1SMN1; SMN2SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109952289-A | TRPV4 antagonist | 葛兰素史密斯克莱知识产权（第2 号）有限公司 | 2019-06-28 | — | — | CN | claimed |
| CN-106008355-B | Compound and its purposes as BACE inhibitor | 阿斯利康(瑞典)有限公司 | 2019-05-03 | — | — | CN | claimed |
| CN-109952289-A | TRPV4 antagonist | 葛兰素史密斯克莱知识产权（第2 号）有限公司 | 2019-06-28 | — | — | CN | disclosed |
| CN-106008355-B | Compound and its purposes as BACE inhibitor | 阿斯利康(瑞典)有限公司 | 2019-05-03 | — | — | CN | disclosed |
| CN-103380133-B | Compounds and their use as BACE inhibitors | 阿斯利康(瑞典)有限公司 | 2016-06-29 | — | — | CN | disclosed |
| CN-103254137-B | 2-(phenyl of replacement)-6-amino-5-alkoxyl group, thio alkoxy and aminoalkyl group pyrimidine-4-carboxylic acid derivative and the purposes as weedicide thereof | DOW AGROSCIENCES LLC (US) | 2015-09-30 | — | — | CN | disclosed |