Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | LATS1 | O95835 | 1/20 | 0.33 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.32 |
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.31 |
| ▸ | DHODH | Q02127 | 4/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | CHUK | O15111 | 1/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15777428 | 1.00 | RORC (0.34) | RORCLATS1LATS2CA12CA2 | |
| SCHEMBL20481226 | 0.80 | CA12 (0.37) | CA12CA2CA9CA1CA14 | |
| SCHEMBL24200150 | 0.79 | CA12 (0.36) | CA12CA2CA9CA1CA14 | |
| SCHEMBL13724635 | 0.77 | KDM4E (0.36) | CA12CA2CA9CA1CA14 | |
| SCHEMBL15776169 | 0.77 | CA12 (0.33) | CA12CA2CA9CA1CA14 | |
| SCHEMBL527070 | 0.74 | CA12 (0.33) | CA12CA2CA9CA1CA14 | |
| SCHEMBL15475790 | 0.73 | CA12 (0.33) | CA12CA2CA9CA1CA14 | |
| SCHEMBL28715395 | 0.73 | ALPL (0.39) | CA12CA2CA9CA1CA14 | |
| SCHEMBL29421207 | 0.73 | ALPL (0.39) | CA12CA2CA9CA1CA14 | |
| SCHEMBL28026358 | 0.73 | CNR2 (0.44) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104837818-A | Pyridine-2-amides useful as CB2 agonists | HOFFMANN LA ROCHE | 2015-08-12 | — | — | CN | disclosed |