Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | BUB1 | O43683 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29250309 | 0.78 | USP2 (0.42) | BCHECTSKUSP2SMN1; SMN2FAAH | |
| SCHEMBL5773612 | 0.72 | USP2 (0.38) | BCHECTSKUSP2SMN1; SMN2FAAH | |
| SCHEMBL3110325 | 0.71 | NFKB1 (0.36) | BCHEUSP2SMN1; SMN2CHRM2CHRM1 | |
| SCHEMBL27613482 | 0.71 | NR1H2 (0.33) | BCHEUSP2SMN1; SMN2 | |
| SCHEMBL3354765 | 0.69 | USP2 (0.40) | BCHECTSKUSP2SMN1; SMN2FAAH | |
| SCHEMBL5858067 | 0.69 | USP2 (0.40) | BCHECTSKUSP2SMN1; SMN2CHRM2 | |
| SCHEMBL27771573 | 0.69 | BCHE (0.39) | BCHECTSKUSP2SMN1; SMN2FAAH | |
| SCHEMBL29029079 | 0.69 | USP2 (0.36) | BCHECTSKUSP2SMN1; SMN2FAAH | |
| SCHEMBL27868546 | 0.68 | NR1H2 (0.36) | BCHEALDH1A1 | |
| SCHEMBL13803882 | 0.68 | BCHE (0.33) | BCHEUSP2SMN1; SMN2GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104926839-A | Tetrahydroimidazothienothienopyridine hydrochloride compound with biological activity and preparation method thereof | UNIV HENAN NORMAL | 2015-09-23 | — | — | CN | claimed |
| CN-104926839-A | Tetrahydroimidazothienothienopyridine hydrochloride compound with biological activity and preparation method thereof | UNIV HENAN NORMAL | 2015-09-23 | — | — | CN | disclosed |