Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.42 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28026157 | 0.86 | NPC1 (0.50) | NPC1KDM4EKMT2AMEN1RECQL | |
| SCHEMBL1283020 | 0.85 | NPC1 (0.55) | NPC1KDM4EKMT2APTGS2HSD17B10 | |
| SCHEMBL6787728 | 0.85 | KDM4E (0.51) | KDM4EKMT2AMEN1RECQLPTGS2 | |
| SCHEMBL28026634 | 0.84 | NPC1 (0.49) | NPC1KDM4EKMT2AMEN1RECQL | |
| SCHEMBL7952969 | 0.83 | SLC6A3 (0.63) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL1868204 | 0.83 | KDM4E (0.63) | NPC1KDM4EKMT2AMEN1PTGS2 | |
| SCHEMBL16208732 | 0.83 | PKM (0.56) | KDM4EKMT2AMEN1RECQLPTGS2 | |
| SCHEMBL28798171 | 0.83 | MEN1 (0.62) | NPC1KDM4EKMT2AMEN1RECQL | |
| SCHEMBL7952966 | 0.82 | KDM4E (0.49) | KDM4EKMT2AMEN1RECQLPTGS2 | |
| SCHEMBL8587612 | 0.82 | TSHR (0.65) | KDM4EKMT2AMEN1RECQLHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104829757-B | A kind of ingredient of solid catalyst of olefin polymerization acid esters compound containing bigcatkin willow and its preparation method and application | 中国科学院化学研究所 | 2018-04-27 | — | — | CN | disclosed |
| CN-104829757-A | Salicylate-compound-containing solid catalyst component for olefin polymerization, and preparation method and application thereof | CHINESE ACAD INST CHEMISTRY | 2015-08-12 | — | — | CN | disclosed |