SCHEMBL28026643

SCHEMBL28026643

CC(C)Oc1ccccc1C(=O)OC(=O)C(C)(C)C

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IRAK4 Q9NWZ3 2/20 0.57
ELANE P08246 3/20 0.49
KCNK3 O14649 2/20 0.44
KCNK9 Q9NPC2 2/20 0.44
ALDH1A1 P00352 2/20 0.43
ACHE P22303 1/20 0.43
IDO1 P14902 1/20 0.43
TDO2 P48775 1/20 0.43
RXFP1 Q9HBX9 2/20 0.40
PRMT5 O14744 1/20 0.40
HPGD P15428 1/20 0.38
XBP1 P17861 1/20 0.38
MAPT P10636 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
HCRTR1 O43613 1/20 0.38
HCRTR2 O43614 1/20 0.38
KDM4E B2RXH2 2/20 0.38
LMNA P02545 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
HTR2A P28223 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27958806 0.87 IRAK4 (0.68) IRAK4KCNK3KCNK9ALDH1A1ACHE
SCHEMBL4332049 0.83 IRAK4 (0.64) IRAK4KCNK3KCNK9ALDH1A1ACHE
SCHEMBL28026162 0.81 IRAK4 (0.60) IRAK4KCNK3KCNK9ALDH1A1ACHE
SCHEMBL17863859 0.80 IRAK4 (0.64) IRAK4ELANEKCNK3KCNK9ALDH1A1
SCHEMBL27568908 0.79 IRAK4 (0.58) IRAK4KCNK3KCNK9ALDH1A1ACHE
SCHEMBL13251737 0.79 HSD17B10 (0.59) ELANEALDH1A1HPGDMAPTNPSR1
SCHEMBL4036585 0.78 IRAK4 (0.66) IRAK4KCNK3KCNK9ALDH1A1ACHE
SCHEMBL2942817 0.78 IRAK4 (0.66) IRAK4KCNK3KCNK9ALDH1A1ACHE
SCHEMBL28020534 0.78 IRAK4 (0.57) IRAK4ELANEKCNK3KCNK9ALDH1A1
SCHEMBL11985721 0.77 IRAK4 (0.55) IRAK4ELANEKCNK3KCNK9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104829757-B A kind of ingredient of solid catalyst of olefin polymerization acid esters compound containing bigcatkin willow and its preparation method and application 中国科学院化学研究所 2018-04-27 CN disclosed
CN-104829757-A Salicylate-compound-containing solid catalyst component for olefin polymerization, and preparation method and application thereof CHINESE ACAD INST CHEMISTRY 2015-08-12 CN disclosed