Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28026655 | 0.92 | ALDH1A1 (0.59) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL28026176 | 0.91 | TSHR (0.60) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL28026651 | 0.90 | TSHR (0.58) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL28026719 | 0.86 | ALDH1A1 (0.55) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL28026673 | 0.85 | ALDH1A1 (0.54) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL11316554 | 0.84 | ALDH1A1 (0.67) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL1282684 | 0.83 | TSHR (0.73) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL5158365 | 0.82 | TSHR (0.71) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL5158356 | 0.82 | TSHR (0.71) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL1870045 | 0.82 | TSHR (0.71) | TSHRTDP1L3MBTL1MAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104829757-A | Salicylate-compound-containing solid catalyst component for olefin polymerization, and preparation method and application thereof | CHINESE ACAD INST CHEMISTRY | 2015-08-12 | — | — | CN | disclosed |