SCHEMBL1870045

SCHEMBL1870045

CCCCOC(=O)c1ccccc1OC(C)=O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.71
TDP1 Q9NUW8 3/20 0.71
L3MBTL1 Q9Y468 2/20 0.71
PTGS2 P35354 8/20 0.67
MAPK1 P28482 3/20 0.64
CYP3A4 P08684 2/20 0.64
TP53 P04637 1/20 0.64
ALDH1A1 P00352 7/20 0.62
LMNA P02545 2/20 0.62
HSD17B10 Q99714 4/20 0.61
KDM4E B2RXH2 3/20 0.56
CYP1A2 P05177 1/20 0.56
CYP2C9 P11712 1/20 0.56
POLB P06746 1/20 0.55
ESR1 P03372 1/20 0.54
ITGB3 P05106 1/20 0.54
ITGA2B P08514 1/20 0.54
HMGB1 P09429 1/20 0.54
HPGD P15428 1/20 0.54
GGT1 P19440 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27528077 0.95 TSHR (0.71) TSHRTDP1L3MBTL1PTGS2MAPK1
SCHEMBL4730460 0.94 ALDH1A1 (0.72) TSHRTDP1L3MBTL1PTGS2MAPK1
SCHEMBL11314352 0.94 ALDH1A1 (0.72) TSHRTDP1L3MBTL1PTGS2MAPK1
SCHEMBL4732320 0.94 ALDH1A1 (0.72) TSHRTDP1L3MBTL1PTGS2MAPK1
SCHEMBL4728775 0.94 ALDH1A1 (0.72) TSHRTDP1L3MBTL1PTGS2MAPK1
SCHEMBL4728781 0.94 ALDH1A1 (0.72) TSHRTDP1L3MBTL1PTGS2MAPK1
SCHEMBL11985699 0.92 PTGS2 (0.72) TSHRTDP1L3MBTL1PTGS2MAPK1
SCHEMBL12715080 0.91 PTGS2 (0.75) TSHRTDP1L3MBTL1PTGS2MAPK1
SCHEMBL9446603 0.91 PTGS2 (0.75) TSHRTDP1L3MBTL1PTGS2MAPK1
SCHEMBL4782034 0.91 ALDH1A1 (0.69) TSHRTDP1L3MBTL1PTGS2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2994505-B1 A PROCESS FOR DEPOLYMERIZATION OF LIGNIN COUNCIL SCIENT IND RES (IN) 2017-04-05 EP claimed
US-9550710-B2 Process for depolymerization of lignin COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2017-01-24 US claimed
US-20160168062-A1 PROCESS FOR DEPOLYMERIZATION OF LIGNIN COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2016-06-16 US claimed
EP-2994505-A1 A PROCESS FOR DEPOLYMERIZATION OF LIGNIN Council of Scientific & Industrial Research (IN) 2016-03-16 EP claimed
WO-2014181360-A1 A PROCESS FOR DEPOLYMERIZATION OF LIGNIN COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2014-11-13 WO claimed
CN-104829757-B A kind of ingredient of solid catalyst of olefin polymerization acid esters compound containing bigcatkin willow and its preparation method and application 中国科学院化学研究所 2018-04-27 CN disclosed
EP-3173072-A1 CONVENIENTLY IMPLANTABLE SUSTAINED RELEASE DRUG COMPOSITIONS Ramscor, Inc. (US) 2017-05-31 EP disclosed
EP-2994505-B1 A PROCESS FOR DEPOLYMERIZATION OF LIGNIN COUNCIL SCIENT IND RES (IN) 2017-04-05 EP disclosed
US-9550710-B2 Process for depolymerization of lignin COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2017-01-24 US disclosed
US-20160168062-A1 PROCESS FOR DEPOLYMERIZATION OF LIGNIN COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2016-06-16 US disclosed
EP-2994505-A1 A PROCESS FOR DEPOLYMERIZATION OF LIGNIN Council of Scientific & Industrial Research (IN) 2016-03-16 EP disclosed
US-20150273066-A1 CONVENIENTLY IMPLANTABLE SUSTAINED RELEASE DRUG COMPOSITIONS RAMSCOR INC (US) 2015-10-01 US disclosed
US-20080038316-A1 Conveniently implantable sustained release drug compositions RAMSCOR, INC. 2008-02-14 US disclosed
EP-1793803-A2 CONVENIENTLY IMPLANTABLE SUSTAINED RELEASE DRUG COMPOSITIONS Ramscor, Inc. (US) 2007-06-13 EP disclosed
WO-2006039336-A2 CONVENIENTLY IMPLANTABLE SUSTAINED RELEASE DRUG COMPOSITIONS RAMSCOR, INC. (US) 2006-04-13 WO disclosed
US-20060073182-A1 Conveniently implantable sustained release drug compositions RAMSCOR, INC. 2006-04-06 US disclosed
US-4287174-A CONTAINING A QUATERNARY AMMONIUM CARBOXY ZWITTERIONIC COMPOUND AND AN ANTACID THE PROCTOR & GAMBLE COMPANY (US) 1981-09-01 US disclosed
US-4275059-A IN COMBINATION WITH A DIPHOSPHONATE COMPOUND THE PROCTER & GAMBLE COMPANY (US) 1981-06-23 US disclosed
US-4199576-A DERIVATIVES OF SALICYCLIC ACID THE PROCTER & GAMBLE COMPANY (US) 1980-04-22 US disclosed
EP-0004686-A2 Anti-ulcer composition THE PROCTER & GAMBLE COMPANY (US) 1979-10-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160168062-A1 PROCESS FOR DEPOLYMERIZATION OF LIGNIN DCXR, BROX, LCT TSHR 4864/4885TDP1 2699/4885L3MBTL1 923/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.