Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 5/20 | 0.44 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28026719 | 0.96 | ALDH1A1 (0.55) | ALDH1A1TSHRCYP3A4MAPK1TP53 | |
| SCHEMBL28026651 | 0.95 | TSHR (0.58) | ALDH1A1TSHRCYP3A4MAPK1TP53 | |
| SCHEMBL28026176 | 0.91 | TSHR (0.60) | ALDH1A1TSHRCYP3A4MAPK1TP53 | |
| SCHEMBL28026655 | 0.87 | ALDH1A1 (0.59) | ALDH1A1TSHRCYP3A4MAPK1TP53 | |
| SCHEMBL28026649 | 0.85 | TSHR (0.61) | ALDH1A1TSHRCYP3A4MAPK1TP53 | |
| SCHEMBL28026627 | 0.84 | KDM4E (0.44) | ALDH1A1TSHRCYP3A4MAPK1TP53 | |
| SCHEMBL11316554 | 0.82 | ALDH1A1 (0.67) | ALDH1A1TSHRCYP3A4MAPK1TP53 | |
| SCHEMBL28026640 | 0.80 | KDM4E (0.45) | ALDH1A1TSHRCYP3A4MAPK1TP53 | |
| SCHEMBL5706286 | 0.79 | TSHR (0.68) | ALDH1A1TSHRCYP3A4MAPK1TP53 | |
| SCHEMBL1282581 | 0.78 | ALDH1A1 (0.71) | ALDH1A1TSHRCYP3A4MAPK1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104829757-A | Salicylate-compound-containing solid catalyst component for olefin polymerization, and preparation method and application thereof | CHINESE ACAD INST CHEMISTRY | 2015-08-12 | — | — | CN | disclosed |