Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PTPRG | P23470 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28026661 | 1.00 | KMT2A (0.52) | KMT2AMEN1L3MBTL1HTTPTPRG | |
| SCHEMBL2543970 | 0.85 | KMT2A (0.52) | KMT2AMEN1L3MBTL1HTTPTPRG | |
| SCHEMBL2543968 | 0.85 | KMT2A (0.52) | KMT2AMEN1L3MBTL1HTTPTPRG | |
| SCHEMBL28027193 | 0.84 | CA12 (0.44) | KMT2AMEN1L3MBTL1HTTNPSR1 | |
| SCHEMBL28027191 | 0.84 | CA12 (0.44) | KMT2AMEN1L3MBTL1HTTNPSR1 | |
| SCHEMBL28026693 | 0.80 | ALDH1A1 (0.45) | KMT2AMEN1L3MBTL1HTTPOLB | |
| SCHEMBL28026689 | 0.80 | ALDH1A1 (0.45) | KMT2AMEN1L3MBTL1HTTPOLB | |
| SCHEMBL21678168 | 0.76 | STS (0.57) | KMT2AMEN1HTTLMNAKDM4E | |
| SCHEMBL1901284 | 0.76 | PTPRG (0.67) | KMT2AMEN1L3MBTL1HTTPTPRG | |
| SCHEMBL11729716 | 0.76 | KMT2A (0.64) | KMT2AMEN1L3MBTL1HTTPTPRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102858778-B | Heterobiaryl-cyclohexyl-tetrazine is [e] Azulene also | HOFFMAN-LA ROCHE LTD. (CH) | 2015-08-26 | — | — | CN | disclosed |