Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27621910 | 0.79 | SMN1; SMN2 (0.32) | SMN1; SMN2NTRK1ALDH1A1RECQLRAB9A | |
| SCHEMBL1208751 | 0.69 | — | — | |
| SCHEMBL2616829 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL14119534 | 0.67 | KMT2A (0.34) | SMN1; SMN2NTRK1ALDH1A1RECQLRAB9A | |
| SCHEMBL18759809 | 0.67 | NTRK1 (0.46) | SMN1; SMN2GAANTRK1ALDH1A1RECQL | |
| SCHEMBL22642775 | 0.64 | COMT (0.37) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL454739 | 0.63 | — | — | |
| SCHEMBL9750640 | 0.60 | NOS1 (0.45) | SMN1; SMN2GAAALDH1A1RAB9A | |
| SCHEMBL24664333 | 0.58 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL19987805 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104758281-A | Chemicals, compositions, and methods for treatment and prevention of orthopoxvirus infections and associated diseases | SIGA TECHNOLOGIES INC | 2015-07-08 | — | — | CN | disclosed |