Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11294109 | 0.71 | KDM4E (0.39) | SMN1; SMN2 | |
| SCHEMBL27766866 | 0.71 | HSP90AA1 (0.45) | HSP90AA1HSP90AB1POLBGAAMAPT | |
| SCHEMBL28026930 | 0.70 | NOS3 (0.36) | SMN1; SMN2 | |
| SCHEMBL9476338 | 0.68 | ALDH1A1 (0.46) | HSP90AA1HSP90AB1POLBGAAMAPT | |
| SCHEMBL5746102 | 0.67 | ALDH1A1 (0.40) | POLBGAAMAPTSMN1; SMN2 | |
| SCHEMBL30421541 | 0.67 | ALDH1A1 (0.40) | POLBGAAMAPTSMN1; SMN2 | |
| SCHEMBL11294439 | 0.67 | S1PR2 (0.31) | HSP90AA1HSP90AB1 | |
| SCHEMBL259983 | 0.66 | TDP1 (0.48) | HSP90AA1HSP90AB1GAAMAPT | |
| SCHEMBL29462391 | 0.66 | TDP1 (0.48) | HSP90AA1HSP90AB1GAAMAPT | |
| Hydrochloric Acid SCHEMBL5778836 | 0.65 | TDP1 (0.46) | HSP90AA1HSP90AB1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104755465-A | Heterocyclic compounds | TAKEDA PHARMACEUTICAL | 2015-07-01 | — | — | CN | disclosed |