Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | PTPRC | P08575 | 1/20 | 0.34 |
| ▸ | PTPRF | P10586 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL163967 | 0.83 | SMN1; SMN2 (0.41) | GLRA1TP53LMNAALDH1A1BRD4 | |
| SCHEMBL5222576 | 0.83 | MRGPRX4 (0.46) | GLRA1ALDH1A1MRGPRX4RAB9AFFAR1 | |
| SCHEMBL2133327 | 0.81 | MRGPRX4 (0.49) | TP53LMNAALDH1A1LOXL2MRGPRX4 | |
| SCHEMBL10036558 | 0.81 | GLRA1 (0.41) | GLRA1TP53ALDH1A1PTPRCPTPRF | |
| SCHEMBL5454978 | 0.81 | BRD4 (0.47) | TP53LMNAPOLBTDP1L3MBTL1 | |
| SCHEMBL9821352 | 0.79 | NPC1 (0.43) | GLRA1TP53LMNAALDH1A1POLB | |
| SCHEMBL4572223 | 0.77 | GLRA1 (0.41) | GLRA1TP53ALDH1A1PTPRCPTPRF | |
| SCHEMBL17395798 | 0.77 | BRD4 (0.50) | TP53LMNAPOLBTDP1L3MBTL1 | |
| SCHEMBL3624689 | 0.76 | PRKCE (0.37) | TP53LMNAALDH1A1POLBTDP1 | |
| SCHEMBL27775516 | 0.76 | CA12 (0.39) | TP53LMNAPOLBTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102776218-B | Mutant receptors and their use in a nuclear receptor-based inducible gene expression system | 因特莱克森公司 | 2017-04-12 | — | — | CN | disclosed |
| CN-1964622-B | Mutant receptors and their use in nuclear receptor-based inducible gene expression systems | INTREXON CORP. (US) | 2015-08-26 | — | — | CN | disclosed |